Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MMP14 | P50281 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.49 |
| ▸ | CASP3 | P42574 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | TERT | O14746 | 3/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4293382 | 0.96 | MEN1 (0.54) | MEN1MMP14KMT2AHDAC2CASP3 | |
| SCHEMBL4285958 | 0.90 | CASP3 (0.52) | MEN1MMP14KMT2AHDAC2CASP3 | |
| SCHEMBL4654042 | 0.89 | MAOA (0.56) | MEN1MMP14KMT2AHDAC2CASP3 | |
| SCHEMBL8777783 | 0.86 | MEN1 (0.67) | MEN1MMP14KMT2AHDAC2CASP3 | |
| SCHEMBL15153792 | 0.85 | MEN1 (0.48) | MEN1MMP14KMT2AHDAC2CASP3 | |
| SCHEMBL10728256 | 0.85 | MEN1 (0.52) | MEN1MMP14KMT2AHDAC2CASP3 | |
| SCHEMBL1982461 | 0.82 | MEN1 (0.72) | MEN1MMP14KMT2AHDAC2CASP3 | |
| SCHEMBL30611003 | 0.82 | MEN1 (0.72) | MEN1MMP14KMT2AHDAC2CASP3 | |
| SCHEMBL4305458 | 0.81 | MEN1 (0.76) | MEN1MMP14KMT2AHDAC2CASP3 | |
| SCHEMBL10726032 | 0.81 | MEN1 (0.56) | MEN1MMP14KMT2AHDAC2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023068316-A1 | MATERIAL FOR SOFT CONTACT LENS HAVING CONTRAST IMPROVEMENT FUNCTION | 興和株式会社 | 2023-04-27 | — | — | WO | disclosed |
| US-20210163650-A1 | POLYMER MATERIAL | MENICON CO., LTD. (JP) | 2021-06-03 | — | — | US | disclosed |
| EP-3822296-A1 | POLYMER MATERIAL | Menicon Co., Ltd. (JP) | 2021-05-19 | — | — | EP | disclosed |
| CN-104284942-A | Stable polymerizable UV-absorbing colorant for intraocular lens | KOWA CO | 2015-01-14 | — | — | CN | disclosed |
| EP-2581394-A1 | IONIC COMPOUND, COMPOSITION, CURED PRODUCT, HYDROGEL, AND OCULAR LENS | Menicon Co., Ltd. (JP) | 2013-04-17 | — | — | EP | disclosed |
| EP-1696257-B1 | CONTACT LENS MATERIAL | MENICON CO LTD (JP) | 2012-11-21 | — | — | EP | disclosed |
| US-20090247662-A1 | Contact Lens Material | MATSUMOTO MASAHIRO | 2009-10-01 | — | — | US | disclosed |
| EP-1033590-B1 | Ocular lens material | MENICON CO LTD (JP) | 2008-05-07 | — | — | EP | disclosed |
| US-20070149699-A1 | Contact lens material | MENICON CO., LTD. (JP) | 2007-06-28 | — | — | US | disclosed |
| EP-1696257-A1 | CONTACT LENS MATERIAL | MENICON CO., LTD. (JP) | 2006-08-30 | — | — | EP | disclosed |
| US-6329445-B1 | Ocular lens material | MENICON CO., LTD (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-0947856-A2 | Ocular lens material | Menicon Co., Ltd. (JP) | 1999-10-06 | — | — | EP | disclosed |