Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4005972 | 0.83 | GPR119 (0.46) | HTR6BCHEGPR119KDM4EPKM | |
| SCHEMBL31668267 | 0.79 | HTR6 (0.49) | HTR6BCHEGPR119CHRM2CHRM4 | |
| SCHEMBL4294437 | 0.76 | DPP4 (0.36) | GPR119DPP4 | |
| SCHEMBL4002091 | 0.73 | GPR119 (0.48) | HTR6BCHEGPR119KDM4EPKM | |
| SCHEMBL26119737 | 0.69 | GPR119 (0.44) | HTR6GPR119CHRM2CHRM4CHRM1 | |
| SCHEMBL4151122 | 0.68 | DPP4 (0.39) | GPR119DPP4 | |
| SCHEMBL4306614 | 0.67 | GPR119 (0.44) | GPR119KDM4EPKM | |
| SCHEMBL4171410 | 0.67 | GPR119 (0.43) | GPR119 | |
| SCHEMBL1760744 | 0.67 | MEN1 (0.43) | HTR6BCHECHRM2CHRM4CHRM1 | |
| SCHEMBL4293776 | 0.67 | HCAR1 (0.38) | GPR119DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009079001-A1 | BICYCLIC HETEROARYL-SUBSTITUTED IMIDAZOLES AS MODULATORS OF THE HISTAMINE H4 RECEPTOR | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-06-25 | — | — | WO | disclosed |