Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 4/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4151122 | 0.88 | DPP4 (0.39) | DPP4STSGPR119CNR1NPC1 | |
| SCHEMBL4171410 | 0.84 | GPR119 (0.43) | GPR119 | |
| SCHEMBL4297962 | 0.76 | HTR6 (0.39) | DPP4GPR119 | |
| SCHEMBL31735374 | 0.72 | KDM4E (0.41) | GPR119USP30 | |
| SCHEMBL4293776 | 0.71 | HCAR1 (0.38) | DPP4GPR119 | |
| SCHEMBL4002013 | 0.70 | GPR119 (0.44) | GPR119 | |
| SCHEMBL4155145 | 0.69 | GPR119 (0.43) | GPR119 | |
| SCHEMBL18918197 | 0.68 | KDM4E (0.43) | GPR119ALDH1A1 | |
| SCHEMBL23214885 | 0.68 | MAPT (0.47) | STSGPR119CNR1NPC1ALDH1A1 | |
| SCHEMBL15521929 | 0.67 | ALDH1A1 (0.45) | GPR119ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009079001-A1 | BICYCLIC HETEROARYL-SUBSTITUTED IMIDAZOLES AS MODULATORS OF THE HISTAMINE H4 RECEPTOR | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-06-25 | — | — | WO | disclosed |