Fluoride

Fluoride

SCHEMBL4299936

CCN(CC)c1cccc2c1N2.F

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
CYP3A4 P08684 3/20 0.33
ALDH1A1 P00352 2/20 0.33
DDB1 Q16531 1/20 0.33
CRBN Q96SW2 1/20 0.33
GAA P10253 2/20 0.32
AR P10275 1/20 0.32
GFER P55789 1/20 0.32
CNR2 P34972 1/20 0.32
NPC1 O15118 1/20 0.31
MAPT P10636 1/20 0.31
GRK6 P43250 1/20 0.31
RAB9A P51151 1/20 0.31
HIF1A Q16665 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
TSHR P16473 1/20 0.31
LMNA P02545 1/20 0.30
BRD4 O60885 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL4577949 0.82 CRHR1 (0.33) MEN1KMT2ACYP3A4MAPTNPSR1
SCHEMBL29885903 0.78 ALOX5 (0.48) MEN1KMT2AGAAMAPTNPSR1
SCHEMBL5499929 0.78 ALOX5 (0.48) MEN1KMT2AGAAMAPTNPSR1
SCHEMBL5501861 0.73 KCNH2 (0.39) ALDH1A1GAANPC1RAB9A
Fluoride SCHEMBL4600859 0.72 MEN1 (0.33) MEN1KMT2ACYP3A4ALDH1A1DDB1
SCHEMBL5495887 0.70 CDC25A (0.40) MEN1KMT2AALDH1A1CNR2
SCHEMBL31718395 0.70 TSHR (0.46) MEN1KMT2ACYP3A4ALDH1A1GAA
SCHEMBL6299189 0.70 TSHR (0.46) MEN1KMT2ACYP3A4ALDH1A1GAA
SCHEMBL5500090 0.69 MAPT (0.40) MEN1KMT2ACYP3A4ALDH1A1GAA
SCHEMBL29861910 0.69 L3MBTL1 (0.43) MEN1KMT2ACYP3A4ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113072847-B Thermochromic pavement coating with autonomous temperature regulation function and preparation method thereof 同济大学 2022-08-30 CN claimed
CN-111604014-B Preparation method of color-changing microcapsule capable of being applied to textile and color-changing microcapsule 福建拓烯新材料科技有限公司 2022-04-19 CN claimed
CN-113072847-A Thermochromic pavement coating with autonomous temperature regulation function and preparation method thereof 同济大学 2021-07-06 CN claimed
CN-111604014-A Preparation method of color-changing microcapsule capable of being applied to textile and color-changing microcapsule 福建拓烯新材料科技有限公司 2020-09-01 CN claimed
CN-111607972-A Temperature-sensitive color-changing microcapsule for fabric and preparation method thereof 福建拓烯新材料科技有限公司 2020-09-01 CN claimed
EP-0136678-B1 HEAT SENSITIVE RECORD MATERIAL HODOGAYA CHEMICAL CO., LTD. (JP) 1989-09-13 EP claimed
JP-57202348-A None JP disclosed
CN-117619285-A Preparation method of thermochromic microcapsule and thermochromic ink 福建泰新泉科技有限公司 2024-03-01 CN disclosed
CN-113072847-B Thermochromic pavement coating with autonomous temperature regulation function and preparation method thereof 同济大学 2022-08-30 CN disclosed
CN-111604014-B Preparation method of color-changing microcapsule capable of being applied to textile and color-changing microcapsule 福建拓烯新材料科技有限公司 2022-04-19 CN disclosed
CN-114316941-A High-stability quaternary hydrophilic bionic organic thermochromatic system 天津大学 2022-04-12 CN disclosed
CN-113072847-A Thermochromic pavement coating with autonomous temperature regulation function and preparation method thereof 同济大学 2021-07-06 CN disclosed
CN-111604014-A Preparation method of color-changing microcapsule capable of being applied to textile and color-changing microcapsule 福建拓烯新材料科技有限公司 2020-09-01 CN disclosed
US-20030022092-A1 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. 2003-01-30 US disclosed
US-20030013608-A1 Thermal recording material FUJI PHOTO FILM CO., LTD. 2003-01-16 US disclosed
US-6465392-B1 HEAT-SENSITIVE RECORDING MATERIAL INCLUDING A HEAT-SENSITIVE RECORDING LAYER AND A PROTECTIVE LAYER PROVIDED ON A SUBSTRATE; EXCELLENT SCRATCH RESISTANCE AND CAUSES NO STICKING AND RESIDUE ADHESION AT A HEAT-SENSITIVE RECORDING HEAD FUJI PHOTO FILM CO., LTD. (JP) 2002-10-15 US disclosed
US-4985331-A Multi-color recording materials FUJI PHOTO FILM CO., LTD. (JP) 1991-01-15 US disclosed
US-4758547-A Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1988-07-19 US disclosed
US-4583104-A Recording materials FUJI PHOTO FILM CO., LTD. (JP) 1986-04-15 US disclosed
JP-S57202348-A FLUORANE DERIVATIVE AND RECORDING MATERIAL CONTAINING THE SAME FUJI PHOTO FILM CO LTD 1982-12-11 JP disclosed