Fluoride

Fluoride

SCHEMBL4600859

CCN(CC)c1cccc2c1CN2.F

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
DDB1 Q16531 1/20 0.31
CRBN Q96SW2 1/20 0.31
ALDH1A1 P00352 2/20 0.31
CYP3A4 P08684 1/20 0.31
KDM4E B2RXH2 1/20 0.30
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
THRB P10828 1/20 0.30
ALOX15 P16050 1/20 0.30
CASP1 P29466 1/20 0.30
HTT P42858 1/20 0.30
CASP7 P55210 1/20 0.30
HSD17B10 Q99714 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
ADRA2A P08913 1/20 0.30
ADRA2B P18089 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL4299936 0.72 MEN1 (0.35) MEN1KMT2ADDB1CRBNALDH1A1
Fluoride SCHEMBL11125369 0.67 CRHR1 (0.35) MEN1KMT2AALDH1A1GAAMAPT
SCHEMBL31718395 0.66 TSHR (0.46) MEN1KMT2AALDH1A1CYP3A4LMNA
SCHEMBL6299189 0.66 TSHR (0.46) MEN1KMT2AALDH1A1CYP3A4LMNA
SCHEMBL1011309 0.66 MAOA (0.34) DDB1CRBNALDH1A1KDM4EGAA
SCHEMBL16559080 0.66 RXRA (0.47) MEN1KMT2AALDH1A1LMNATHRB
SCHEMBL19697741 0.66 RXRA (0.47) MEN1KMT2AALDH1A1LMNATHRB
SCHEMBL29861910 0.65 L3MBTL1 (0.43) MEN1KMT2AALDH1A1CYP3A4KDM4E
SCHEMBL19520878 0.64 NOTUM (0.35) ALDH1A1TP53
SCHEMBL10061692 0.63 KDM4E (0.34) ALDH1A1KDM4EGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1510246-B1 Method and apparatus for emulsification FUJIFILM CORP (JP) 2008-04-16 EP disclosed
EP-1382385-B1 Microcapsule and process for manufacturing the same FUJIFILM CORP (JP) 2007-03-21 EP disclosed
US-6881810-B2 Microcapsule and process for manufacturing the same FUJI PHOTO FILM CO., LTD. (JP) 2005-04-19 US disclosed
US-20050056170-A1 Method and apparatus for emulsification FUJI PHOTO FILM CO., LTD. 2005-03-17 US disclosed
EP-1510246-A2 Method and apparatus for emulsification Fuji Photo Film Co., Ltd. (JP) 2005-03-02 EP disclosed
US-20040167026-A1 Microcapsule-containing composition, thermal recording material using the same and process of preparing microcapsule-containing composition FUJI PHOTO FILM CO., LTD. 2004-08-26 US disclosed
US-20040121155-A1 Microcapsule and process for manufacturing the same FUJI PHOTO FILM CO., LTD. (JP) 2004-06-24 US disclosed
US-6723482-B2 COMPRISES DIAZO COUPLERS; SUPPRESSES DISCOLORATION OVER TIME WITHOUT DECREASING LIGHT RESISTANCE OF COLOR DEVELOPED PORTION; PRESERVABILITY FUJI PHOTO FILM CO., LTD. (JP) 2004-04-20 US disclosed
EP-1382385-A1 Microcapsule and process for manufacturing the same FUJI PHOTO FILM CO., LTD. (JP) 2004-01-21 EP disclosed
US-20030022092-A1 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. 2003-01-30 US disclosed
US-6465392-B1 HEAT-SENSITIVE RECORDING MATERIAL INCLUDING A HEAT-SENSITIVE RECORDING LAYER AND A PROTECTIVE LAYER PROVIDED ON A SUBSTRATE; EXCELLENT SCRATCH RESISTANCE AND CAUSES NO STICKING AND RESIDUE ADHESION AT A HEAT-SENSITIVE RECORDING HEAD FUJI PHOTO FILM CO., LTD. (JP) 2002-10-15 US disclosed
US-4985331-A Multi-color recording materials FUJI PHOTO FILM CO., LTD. (JP) 1991-01-15 US disclosed
US-4583104-A Recording materials FUJI PHOTO FILM CO., LTD. (JP) 1986-04-15 US disclosed