Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | TK2 | O00142 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4307219 | 0.83 | LMNA (0.44) | TK1LMNASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL12988358 | 0.81 | TK1 (0.42) | TK1LMNASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL2636826 | 0.80 | LMNA (0.45) | TK1LMNASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL18190788 | 0.76 | DNMT1 (0.39) | TK1LMNASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL31565646 | 0.74 | PYGM (0.41) | LMNA | |
| SCHEMBL23892079 | 0.72 | TK1 (0.41) | TK1LMNASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL12642442 | 0.72 | TK1 (0.41) | TK1LMNASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL658719 | 0.72 | TK1 (0.41) | TK1LMNASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL2641583 | 0.72 | TK1 (0.41) | TK1LMNASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL29973585 | 0.71 | PYGM (0.36) | SMN1; SMN2TK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9803240-B2 | Stabilized nucleic acid dark quencher-fluorophore probes | BIOSEARCH TECHNOLOGIES, INC. (US) | 2017-10-31 | — | — | US | disclosed |
| US-9803240-B2 | Stabilized nucleic acid dark quencher-fluorophore probes | BIOSEARCH TECHNOLOGIES, INC. (US) | 2017-10-31 | — | — | US | disclosed |
| US-20140194611-A1 | STABILIZED NUCLEIC ACID DARK QUENCHER-FLUOROPHORE PROBES | BIOSEARCH TECHNOLOGIES, INC. (US) | 2014-07-10 | — | — | US | disclosed |
| US-20140194611-A1 | STABILIZED NUCLEIC ACID DARK QUENCHER-FLUOROPHORE PROBES | BIOSEARCH TECHNOLOGIES, INC. (US) | 2014-07-10 | — | — | US | disclosed |
| WO-2009129094-A2 | COMPOSITIONS CONTAINING ANTIVIRAL COMPOUNDS AND METHODS OF USING THE SAME | MALLINCKRODT INC. (US) | 2009-10-22 | — | — | WO | disclosed |