SCHEMBL4307219 — predicted protein targets

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	LMNA	P02545	2/20	0.44

▸	SMN1; SMN2	Q16637	2/20	0.44

▸	ALOX12	P18054	1/20	0.39

▸	ADRA1A	P35348	1/20	0.39

▸	TK1	P04183	3/20	0.39

▸	TK2	O00142	1/20	0.36

▸	CYP1A2	P05177	1/20	0.36

▸	CYP3A4	P08684	1/20	0.36

▸	TSHR	P16473	1/20	0.36

▸	BLM	P54132	1/20	0.36

▸	PMP22	Q01453	1/20	0.36

▸	NPSR1	Q6W5P4	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL4300142	0.83	TK1 (0.44)	LMNASMN1; SMN2ALOX12ADRA1ATK1
SCHEMBL2636826	0.83	LMNA (0.45)	LMNASMN1; SMN2ALOX12ADRA1ATK1
SCHEMBL12988358	0.81	TK1 (0.42)	LMNASMN1; SMN2ALOX12ADRA1ATK1
SCHEMBL10873403	0.74	UMPS (0.39)	LMNASMN1; SMN2CYP1A2CYP3A4TSHR
SCHEMBL10873399	0.74	UMPS (0.39)	LMNASMN1; SMN2CYP1A2CYP3A4TSHR
SCHEMBL23892079	0.72	TK1 (0.41)	LMNASMN1; SMN2ALOX12ADRA1ATK1
SCHEMBL12642442	0.72	TK1 (0.41)	LMNASMN1; SMN2ALOX12ADRA1ATK1
SCHEMBL2641583	0.72	TK1 (0.41)	LMNASMN1; SMN2ALOX12ADRA1ATK1
SCHEMBL658719	0.72	TK1 (0.41)	LMNASMN1; SMN2ALOX12ADRA1ATK1
SCHEMBL14088803	0.72	LMNA (0.38)	LMNASMN1; SMN2ALOX12ADRA1ATK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2009129094-A2	COMPOSITIONS CONTAINING ANTIVIRAL COMPOUNDS AND METHODS OF USING THE SAME	MALLINCKRODT INC. (US)	2009-10-22	—	—	WO	disclosed