Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.35 |
| ▸ | PMM2 | O15305 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4307215 | 0.88 | S100A4 (0.37) | PDK1S100A4TRPV1KDM4EMAPK1 | |
| SCHEMBL17361846 | 0.84 | S100A4 (0.42) | PDK1S100A4TRPV1KDM4EMAPK1 | |
| SCHEMBL30558351 | 0.84 | S100A4 (0.42) | PDK1S100A4TRPV1KDM4EMAPK1 | |
| SCHEMBL27839175 | 0.82 | PDK1 (0.44) | PDK1S100A4TRPV1KDM4EMAPK1 | |
| SCHEMBL2318709 | 0.82 | PDK1 (0.54) | PDK1S100A4TRPV1KDM4EMAPK1 | |
| SCHEMBL4435847 | 0.81 | PDK1 (0.41) | PDK1KDM4EMAPK1ALOX12ALOX15 | |
| SCHEMBL17361847 | 0.79 | PDK1 (0.42) | PDK1S100A4TRPV1KDM4EMAPK1 | |
| SCHEMBL4300489 | 0.79 | ALDH1A1 (0.41) | PDK1KDM4EMAPK1PKMRAB9A | |
| SCHEMBL21319 | 0.79 | CASP6 (0.57) | PDK1MEN1KMT2ALMNAACE2 | |
| SCHEMBL2019613 | 0.79 | S100A4 (0.43) | PDK1S100A4TRPV1KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598019-B2 | Method for cleavage of labile functional groups from chemical compounds | UNIVERSITAT KONSTANZ (DE) | 2009-10-06 | — | — | US | disclosed |
| US-7598019-B2 | Method for cleavage of labile functional groups from chemical compounds | UNIVERSITAT KONSTANZ (DE) | 2009-10-06 | — | — | US | disclosed |
| US-20050170281-A1 | Method of cleaving labile functional groups from chemical compounds | NIMBLEGEN SYSTEMS, INC. | 2005-08-04 | — | — | US | disclosed |
| EP-1519941-A2 | A METHOD OF CLEAVING LABILE FUNCTIONAL GROUPS FROM CHEMICAL COMPOUNDS | Chemogenix GmbH (DE) | 2005-04-06 | — | — | EP | disclosed |
| EP-1480927-A2 | A METHOD FOR CLEAVAGE OF LABILE FUNCTIONAL GROUPS FROM CHEMICAL COMPOUNDS | Universität Konstanz (DE) | 2004-12-01 | — | — | EP | disclosed |
| WO-2004089529-A1 | METHOD FOR THE INTRAMOLECULAR ENERGY TRANSFER FOR THE CLEAVAGE OF LABILE FUNCTIONAL GROUP FROM BIOMOLECULES AND THE PROTECTED BIOMOLECULES | Universität Konstanz (DE) | 2004-10-21 | — | — | WO | disclosed |
| WO-2004001033-A2 | A METHOD OF CLEAVING LABILE FUNCTIONAL GROUPS FROM CHEMICAL COMPOUNDS | CHEMOGENIX GMBH (DE) | 2003-12-31 | — | — | WO | disclosed |
| WO-2003074542-A2 | A METHOD FOR CLEAVAGE OF LABILE FUNCTIONAL GROUPS FROM CHEMICAL COMPOUNDS | Universität Konstanz (DE) | 2003-09-12 | — | — | WO | disclosed |