Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1542839 | 0.80 | TRPM8 (0.40) | TRPM8KCNA5ALDH1A1HPGDLMNA | |
| SCHEMBL10949151 | 0.80 | KCNA5 (0.49) | TRPM8KCNA5ALDH1A1HPGDLMNA | |
| SCHEMBL1542834 | 0.78 | P2RX4 (0.44) | TRPM8KCNA5ALDH1A1HPGDLMNA | |
| SCHEMBL16946017 | 0.77 | TRPV1 (0.55) | TRPM8KCNA5TRPV1EPHX1 | |
| SCHEMBL30835092 | 0.77 | TRPM8 (0.50) | TRPM8KCNA5ALDH1A1HPGDLMNA | |
| SCHEMBL2674934 | 0.75 | EPHX1 (0.50) | TRPM8KCNA5ALDH1A1HPGDTRPV1 | |
| SCHEMBL10537190 | 0.74 | TRPV1 (0.48) | TRPM8KCNA5ALDH1A1HPGDLMNA | |
| SCHEMBL31752168 | 0.74 | TRPV1 (0.48) | TRPM8KCNA5ALDH1A1HPGDLMNA | |
| SCHEMBL6129335 | 0.74 | TRPM8 (0.43) | TRPM8KCNA5ALDH1A1HPGDLMNA | |
| SCHEMBL13681469 | 0.73 | OPRD1 (0.49) | TRPM8ALDH1A1LMNAPTGDR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8871288-B2 | Aromatic neomenthylamides as flavoring substances | SYMRISE AG (DE) | 2014-10-28 | — | — | US | disclosed |
| US-20090110796-A1 | AROMATIC NEOMENTHYLAMIDES AS FLAVORING SUBSTANCES | SYMRISE GMBH & CO. KG (DE) | 2009-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090110796-A1 | AROMATIC NEOMENTHYLAMIDES AS FLAVORING SUBSTANCES | AOC3, NPR3, AOC2 | TRPM8 1514/4885KCNA5 2023/4885ALDH1A1 162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.