SCHEMBL430199

SCHEMBL430199

CC(C)(C)O[Si](OC(C)(C)C)(c1ccccc1)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.37
ALDH1A1 P00352 2/20 0.34
ALOX15 P16050 1/20 0.34
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
TSHR P16473 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
NR1H2 P55055 2/20 0.31
NR1H3 Q13133 2/20 0.31
CA4 P22748 1/20 0.31
TAAR1 Q96RJ0 2/20 0.30
SLC6A2 P23975 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL703604 0.98 ESR1 (0.37) MAPK1ALDH1A1ALOX15ESR1ESR2
SCHEMBL432711 0.91 MAPK1 (0.34) MAPK1ALDH1A1ALOX15ESR1ESR2
SCHEMBL24442805 0.83 NPSR1 (0.31) MAPK1TSHR
SCHEMBL2498900 0.83 ALDH1A1 (0.43) ALDH1A1TSHR
SCHEMBL2504307 0.82 PAX8 (0.33) ALDH1A1ESR1ESR2TSHRHSD17B10
SCHEMBL707572 0.81 MAPK1 (0.34) MAPK1ALDH1A1ALOX15ESR1ESR2
SCHEMBL191229 0.80 MAPK1 (0.37) MAPK1ALDH1A1ALOX15ESR1ESR2
SCHEMBL704060 0.80 MAPK1 (0.37) MAPK1ALDH1A1ALOX15ESR1ESR2
SCHEMBL2502697 0.79 TP53 (0.41) ALDH1A1TSHRTDP1
SCHEMBL4650377 0.79 MAPK1 (0.39) MAPK1ALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 289 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240262964-A1 METHOD OF PRODUCING SILICONE POLYMER TORAY FINE CHEMICALS CO., LTD. (JP) 2024-08-08 US disclosed
EP-4361201-A1 METHOD FOR PRODUCING SILICONE POLYMER Toray Fine Chemicals Co., Ltd. (JP) 2024-05-01 EP disclosed
CN-117413005-A Process for producing siloxane polymer 东丽精细化工株式会社 2024-01-16 CN disclosed
CN-115244109-B Process for producing siloxane polymer 东丽精细化工株式会社 2023-07-07 CN disclosed
US-20230167244-A1 METHOD OF PRODUCING SILICONE POLYMER TORAY FINE CHEMICALS CO., LTD. (JP) 2023-06-01 US disclosed
EP-4119596-A1 METHOD FOR PRODUCING SILICONE POLYMER Toray Fine Chemicals Co., Ltd. (JP) 2023-01-18 EP disclosed
WO-2022270336-A1 METHOD FOR PRODUCING SILICONE POLYMER 東レ・ファインケミカル株式会社 2022-12-29 WO disclosed
CN-115244109-A Method for producing siloxane polymer 东丽精细化工株式会社 2022-10-25 CN disclosed
US-11033507-B2 Method of synthesis of silica vesicles and use thereof THE UNIVERSITY OF QUEENSLAND (AU) 2021-06-15 US disclosed
US-20210173309-A1 METHOD OF FORMING REVERSED PATTERN AND METHOD OF MANUFACTURING ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2021-06-10 US disclosed
EP-1127929-A2 Composition for film formation, method of film formation, and silica-based film JSR Corporation (JP) 2001-08-29 EP disclosed
EP-1122770-A2 Silica-based insulating film and its manufacture JSR Corporation (JP) 2001-08-08 EP disclosed
US-20010009936-A1 Method of manufacturing material for forming insulating film JSR CORPORATION (JP) 2001-07-26 US disclosed
EP-1117102-A2 Method of manufacturing material for forming insulating film JSR Corporation (JP) 2001-07-18 EP disclosed
US-6235101-B1 SILICON HYDROLYZATE, METAL CHELATE, ORGANIC SOLVENT AND BETA DIKETONE FOR FILMS JSR CORPORATION (JP) 2001-05-22 US disclosed
EP-1090967-A2 Composition for film formation, method of film formation, and insulating film JSR Corporation (JP) 2001-04-11 EP disclosed
EP-1088868-A2 Composition for film formation, method of film formation, and insulating film JSR Corporation (JP) 2001-04-04 EP disclosed
EP-1058274-A1 Composition for film formation and material for insulating film formation JSR Corporation (JP) 2000-12-06 EP disclosed
EP-1045290-A2 Composition for resist underlayer film and method for producing the same JSR Corporation (JP) 2000-10-18 EP disclosed
EP-0921561-A2 Composition for film formation and film JSR Corporation (JP) 1999-06-09 EP disclosed