Trolamine

Trolamine

SCHEMBL430288

CCCCCCCCC=CCCCCCCCC(=O)OS(=O)(=O)O.OCCN(CCO)CCO

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CNR2 P34972 1/20 0.51
▸ DGKA P23743 1/20 0.47
▸ MGLL Q99685 1/20 0.46
▸ FAAH O00519 3/20 0.46
▸ EPHX2 P34913 1/20 0.46
▸ TERT O14746 3/20 0.45
▸ PTPN1 P18031 3/20 0.45
▸ PPARG P37231 3/20 0.45
▸ PPARD Q03181 3/20 0.45
▸ PPARA Q07869 3/20 0.45
▸ CYP1A2 P05177 2/20 0.45
▸ MAPT P10636 2/20 0.45
▸ CYP2C19 P33261 2/20 0.45
▸ BLM P54132 2/20 0.45
▸ HSD17B10 Q99714 2/20 0.45
▸ FABP4 P15090 2/20 0.45
▸ KMT2A Q03164 2/20 0.45
▸ GMNN O75496 1/20 0.45
▸ USP2 O75604 1/20 0.45
▸ LMNA P02545 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trolamine SCHEMBL27920333 1.00 CNR2 (0.51) CNR2DGKAMGLLFAAHEPHX2
Trolamine SCHEMBL4397943 0.92 DNM1 (0.44) CNR2DGKAMAPTKMT2ALMNA
SCHEMBL8922997 0.89 TERT (0.56) CNR2FAAHEPHX2TERTPTPN1
SCHEMBL29166 0.89 TERT (0.56) CNR2FAAHEPHX2TERTPTPN1
SCHEMBL18123884 0.89 TERT (0.56) CNR2FAAHEPHX2TERTPTPN1
SCHEMBL6860184 0.89 TERT (0.56) CNR2FAAHEPHX2TERTPTPN1
SCHEMBL972972 0.89 TERT (0.56) CNR2FAAHEPHX2TERTPTPN1
SCHEMBL1240696 0.89 TERT (0.56) CNR2FAAHEPHX2TERTPTPN1
SCHEMBL459857 0.87 TERT (0.54) CNR2FAAHEPHX2TERTPTPN1
SCHEMBL1094531 0.87 TERT (0.54) CNR2FAAHEPHX2TERTPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3610849-B1 METHOD FOR REMOVING KERATOTIC PLUGS KAO CORP (JP) 2025-09-17 — — EP disclosed
EP-4023304-B1 A KERATOTIC PLUG-REMOVING COMPOSITION KAO CORP (JP) 2025-08-27 — — EP disclosed
EP-3610848-B1 SKIN CLEANSING COMPOSITION KAO CORP (JP) 2025-08-27 — — EP disclosed
US-11975086-B2 Method for removing keratotic plugs KAO CORPORATION (JP) 2024-05-07 — — US disclosed
EP-4269549-A2 SKIN CLEANSING COMPOSITIONS Kao Corporation (JP) 2023-11-01 — — EP disclosed
EP-3610850-B1 SKIN CLEANSING COMPOSITIONS KAO CORP (JP) 2023-10-25 — — EP disclosed
CN-116847871-A Skin care compositions and methods of use 现代牧场股份有限公司 2023-10-03 — — CN disclosed
CN-116785188-A Skin cleansing composition 花王株式会社 2023-09-22 — — CN disclosed
CN-110520102-B Skin cleansing composition 花王株式会社 2023-08-22 — — CN disclosed
CN-110494120-B Method for removing corner bolts 花王株式会社 2023-07-18 — — CN disclosed
WO-2006033476-A1 HYDROXYCITRIC ACID DERIVATIVES AND SKIN EXTERNAL PREPARATIONS CONTAINING THE SAME SHOWA DENKO K.K. (JP) 2006-03-30 — — WO disclosed
WO-2005115326-A1 TOPICAL SLIMMING PREPARATION AND A COSMETIC CONTAINING A CARNITINE DERIVATIVE SHOWA DENKO K.K. (JP) 2005-12-08 — — WO disclosed
WO-2005102267-A1 AGENT FOR SKIN EXTERNAL USE CONTAINING TOCOPHEROL DERIVATIVE, ASCORBIC ACID DERIVATIVE AND SURFACE ACTIVE AGENT HAVING LIPOPEPTIDE STRUCTURE SHOWA DENKO K.K. (JP) 2005-11-03 — — WO disclosed
WO-2005094777-A1 EXTERNAL PREPARATION FOR SKIN SHOWA DENKO K.K. (JP) 2005-10-13 — — WO disclosed
WO-2005095462-A1 MOISTURE RETENTION POLYMER COMPOUND SHOWA DENKO K.K. (JP) 2005-10-13 — — WO disclosed
US-20050220744-A1 Polysaccharide/functional compound complex SHOWA DENKO K.K. 2005-10-06 — — US disclosed
WO-2005092285-A1 A SKIN CARE AND COSMETIC PREPARATION CONTAINING AN INOSITOL DERIVATIVE SHOWA DENKO K.K. (JP) 2005-10-06 — — WO disclosed
WO-2005089708-A1 OIL-IN-WATER EMULSIFIED COMPOSITION, AND EXTERNAL PREPARATION FOR SKIN AND COSMETICS USING THE COMPOSITION SHOWA DENKO K.K. (JP) 2005-09-29 — — WO disclosed
WO-2005034903-A1 AGENT FOR SKIN EXTERNAL USE CONTAINING SALT OF ASCORBIC ACID DERIVATIVE, METHOD FOR STABILIZING THE AGENT FOR SKIN EXTERNAL USE, AND STABILIZER SHOWA DENKO K.K. (JP) 2005-04-21 — — WO disclosed
WO-2005020950-A1 COSMETIC COMPOSITION COMPRISING A AND A LIPOPEPTIDE SHOWA DENKO K.K. (JP) 2005-03-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11975086-B2 Method for removing keratotic plugs PAM, MUC1, CUTA CNR2 450/4885DGKA 1530/4885MGLL 2097/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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