Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | AKR1B10 | O60218 | 6/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 6/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4292453 | 1.00 | POLB (0.43) | POLBAKR1B10AKR1B1EPHX2MIF | |
| SCHEMBL2886569 | 0.98 | EPHX2 (0.45) | POLBAKR1B10AKR1B1EPHX2MIF | |
| SCHEMBL29569054 | 0.82 | MMP2 (0.54) | AKR1B1EPHX2HPGDMEN1KMT2A | |
| SCHEMBL9436016 | 0.81 | KDM4E (0.54) | POLBAKR1B10AKR1B1MIFKDM4E | |
| SCHEMBL4292444 | 0.77 | MIF (0.44) | AKR1B10AKR1B1MIFKDM4EALDH1A1 | |
| Arachidonic Acid SCHEMBL28529406 | 0.77 | ALDH1A1 (0.56) | AKR1B1EPHX2KDM4EALDH1A1HPGD | |
| SCHEMBL4251337 | 0.76 | HSD17B3 (0.54) | POLBMIFKDM4EALDH1A1HPGD | |
| Water SCHEMBL27385678 | 0.75 | HSD17B3 (0.52) | POLBMIFKDM4EALDH1A1HPGD | |
| SCHEMBL4527127 | 0.75 | HSD17B3 (0.55) | POLBAKR1B10AKR1B1MIFKDM4E | |
| SCHEMBL27844746 | 0.73 | GAA (0.58) | POLBAKR1B10AKR1B1MIFKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090311723-A1 | FLUORESCENCE-BASED ASSAY FOR MONOACYLGLYCEROL LIPASE COMPATIBLE WITH INHIBITOR SCREENING | WYETH (US) | 2009-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090311723-A1 | FLUORESCENCE-BASED ASSAY FOR MONOACYLGLYCEROL LIPASE COMPATIBLE WITH INHIBITOR SCREENING | MGLL, LIPC, LIPA | POLB 4665/4885AKR1B10 1017/4885AKR1B1 923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.