Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4314163 | 0.78 | CYP2A6 (0.33) | CYP2A6TDP1CYP1A2HSP90AA1PAX8 | |
| Hydrochloric Acid SCHEMBL7599358 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL812105 | 0.76 | CYP11B1 (0.33) | — | |
| SCHEMBL4305061 | 0.76 | CYP2A6 (0.34) | CYP2A6TDP1CYP1A2HSP90AA1PAX8 | |
| Hydrochloric Acid SCHEMBL7705066 | 0.74 | GAA (0.33) | CYP1A2HSP90AA1 | |
| Hydrochloric Acid SCHEMBL4094393 | 0.74 | MAOA (0.33) | — | |
| Hydrochloric Acid SCHEMBL5512606 | 0.74 | CYP2A6 (0.31) | CYP2A6TDP1 | |
| Hydrochloric Acid SCHEMBL28994366 | 0.73 | ACHE (0.32) | CYP2A6CYP1A2 | |
| Iodide SCHEMBL27948761 | 0.72 | LMNA (0.31) | — | |
| Bromide SCHEMBL7203730 | 0.72 | HTR2A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009131081-A1 | RESIN COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-10-29 | — | — | WO | disclosed |