Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | ETV6 | P41212 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4666095 | 0.88 | HSP90AA1 (0.39) | L3MBTL3L3MBTL1CDC7CDK9FAAH | |
| SCHEMBL4135754 | 0.83 | HRH3 (0.42) | L3MBTL3PDE4DFAAHHRH3ALDH1A1 | |
| SCHEMBL4137087 | 0.83 | HTR1D (0.41) | L3MBTL3L3MBTL1FAAHHTR1DOPRL1 | |
| SCHEMBL4771706 | 0.81 | AXL (0.37) | L3MBTL3L3MBTL1CDC7CDK9FAAH | |
| SCHEMBL4132414 | 0.81 | HRH3 (0.45) | L3MBTL3L3MBTL1FAAHTP53BP1HTR1D | |
| SCHEMBL4140118 | 0.81 | TDP2 (0.45) | L3MBTL3L3MBTL1FAAHHTR1DHRH3 | |
| SCHEMBL4144270 | 0.81 | TDP2 (0.45) | L3MBTL3L3MBTL1FAAHHTR1DHRH3 | |
| SCHEMBL4140115 | 0.81 | TDP2 (0.45) | L3MBTL3L3MBTL1FAAHHTR1DHRH3 | |
| SCHEMBL4133407 | 0.80 | HTR1A (0.43) | FAAHHTR1DOPRL1KCNH2 | |
| SCHEMBL4136102 | 0.80 | FAAH (0.44) | L3MBTL3L3MBTL1FAAHTP53BP1ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090163482-A1 | TETRALINES ANTAGONISTS OF THE H-3 RECEPTOR | MCHARDY STANTON FURST | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163482-A1 | TETRALINES ANTAGONISTS OF THE H-3 RECEPTOR | HRH3, HRH4, HRH1 | L3MBTL3 3062/4885L3MBTL1 3712/4885MKNK1 4068/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.