Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 2/20 | 0.31 |
| ▸ | GABRD | O14764 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1077474 | 0.83 | — | — | |
| SCHEMBL1756137 | 0.83 | — | — | |
| Phosphoric Acid SCHEMBL16109729 | 0.79 | — | — | |
| SCHEMBL614672 | 0.75 | — | — | |
| SCHEMBL7695671 | 0.75 | — | — | |
| SCHEMBL7160884 | 0.73 | — | — | |
| SCHEMBL8469718 | 0.73 | — | — | |
| Bicarbonate SCHEMBL28148325 | 0.71 | — | — | |
| Bicarbonate SCHEMBL180073 | 0.71 | — | — | |
| SCHEMBL6232434 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090197184-A1 | NON-AQUEOUS ELECTROLYTIC SOLUTION BATTERY AND NON-AQUEOUS ELECTROLYTIC SOLUTION COMPOSITION | SONY CORPORATION (JP) | 2009-08-06 | — | — | US | disclosed |
| US-7491471-B2 | Electrolyte for lithium secondary battery and lithium secondary battery comprising same | SAMSUNG SDI CO., LTD. (KR) | 2009-02-17 | — | — | US | disclosed |
| US-7022878-B2 | such as lithium tetrakis (trifluoroacetate) borate and/or lithium tetrakis (difluoroacetate) borate, having excellent solubility against a nonaqueous solvent; improved electroconductivity | HITACHI, LTD. (JP) | 2006-04-04 | — | — | US | disclosed |
| US-20050171383-A1 | such as lithium tetrakis (trifluoroacetate) borate and/or lithium tetrakis (difluoroacetate) borate, having excellent solubility against a nonaqueous solvent; improved electroconductivity | HITACHI, LTD. (JP) | 2005-08-04 | — | — | US | disclosed |
| US-20050014072-A1 | Electrolyte for lithium secondary battery and lithium secondary battery comprising same | SAMSUNG SDI CO., LTD., A CORPORATION ORGANIZED UNDER THE LAWS OF THE REPUBLIC OF KOREA (KR) | 2005-01-20 | — | — | US | disclosed |
| EP-1498979-A1 | Organic electrolyte for lithium secondary battery and lithium secondary battery comprising same | Samsung SDI Co., Ltd. (KR) | 2005-01-19 | — | — | EP | disclosed |
| US-6824928-B2 | NEW COMPOUND EXCELLENT IN SOLUBILITY AGAINST A NONAQUEOUS SOLVENT, AND THE ELECTROLYTES USING THIS COMPOUND ARE HIGH IN ELECTROCONDUCTIVITY | HITACHI, LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20040053139-A1 | Such as lithium-tetrakis(trifluoroacetate)borate which is highly soluble in solvent of low dielectric constant (ethylene carbonate); improved high-temperature storage; for use in electric appliances/automobiles | HITACHI, LTD. (JP) | 2004-03-18 | — | — | US | disclosed |
| US-20020160273-A1 | Electrolytic cells; mixture of borate and solvent | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2002-10-31 | — | — | US | disclosed |
| EP-1197494-A2 | New organic borate compounds and the nonaqueous electrolytes and lithium secondary batteries using the compounds | Kanto Kagaku Kabushiki Kaisha (JP) | 2002-04-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171383-A1 | such as lithium tetrakis (trifluoroacetate) borate and/or lithium tetrakis (difluoroacetate) borate, having excellent solubility against a nonaqueous solvent; improved electroconductivity | CTCF, NONO, LEF1 | LMNA 3000/4885ALDH1A1 2750/4885TSHR 1925/4885 |
| US-20020160273-A1 | Electrolytic cells; mixture of borate and solvent | RER1, KCNN3, HCN3 | LMNA 3143/4885ALDH1A1 4070/4885TSHR 896/4885 |
| US-20040053139-A1 | Such as lithium-tetrakis(trifluoroacetate)borate which is highly soluble in solvent of low dielectric constant (ethylene carbonate); improved high-temperature storage; for use in electric appliances/automobiles | MCM3, AP3D1, KCNN3 | LMNA 2861/4885ALDH1A1 4534/4885TSHR 763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.