Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | FBP1 | P09467 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 5/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4321800 | 0.87 | P4HB (0.48) | P4HBMEN1LMNAHSP90AA1MAPT | |
| SCHEMBL4989286 | 0.84 | RECQL (0.52) | P4HBMEN1LMNAHSP90AA1MAPT | |
| SCHEMBL28669378 | 0.81 | P4HB (0.48) | P4HBMEN1LMNAHSP90AA1MAPT | |
| SCHEMBL1124018 | 0.80 | LMNA (0.62) | P4HBMEN1LMNAHSP90AA1MAPT | |
| SCHEMBL1124017 | 0.80 | LMNA (0.62) | P4HBMEN1LMNAHSP90AA1MAPT | |
| SCHEMBL27279242 | 0.79 | MAOB (0.48) | P4HBMEN1LMNAHSP90AA1MAPT | |
| SCHEMBL80957 | 0.79 | NFE2L2 (0.56) | P4HBMEN1LMNAHSP90AA1MAPT | |
| SCHEMBL80956 | 0.79 | NFE2L2 (0.56) | P4HBMEN1LMNAHSP90AA1MAPT | |
| SCHEMBL2095432 | 0.79 | FBP1 (0.57) | P4HBMEN1LMNAHSP90AA1MAPT | |
| SCHEMBL2095430 | 0.79 | FBP1 (0.57) | P4HBMEN1LMNAHSP90AA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137338-A1 | PYRAZOLE COMPOUNDS AS CCR1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-11-12 | — | — | WO | disclosed |