Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.47 |
| ▸ | CDC7 | O00311 | 1/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.43 |
| ▸ | TACR1 | P25103 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3759587 | 0.82 | AAK1 (0.38) | KMOCDC7CCNE1CDK2DBF4 | |
| SCHEMBL4307223 | 0.81 | CDC7 (0.48) | KMOCDC7CCNE1CDK2DBF4 | |
| SCHEMBL27473965 | 0.80 | MKNK1 (0.46) | CYP1A2CYP3A4HSD17B10ALDH1A1ALOX15 | |
| SCHEMBL4302003 | 0.80 | SCN9A (0.50) | SCN9ACYP3A4ALDH1A1SCN10AGPBAR1 | |
| SCHEMBL2484725 | 0.78 | PARP1 (0.49) | KMOCDC7CCNE1CDK2DBF4 | |
| SCHEMBL23199045 | 0.77 | NTRK1 (0.52) | CDC7TACR1ALDH1A1MKNK1MKNK2 | |
| SCHEMBL9728870 | 0.76 | NTRK1 (0.65) | KMOCDC7CCNE1CDK2DBF4 | |
| SCHEMBL16487053 | 0.75 | FYN (0.47) | CDC7CYP1A2CYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL27707931 | 0.75 | SCN9A (0.44) | CDC7CCNE1CDK2DBF4SCN9A | |
| Acetic Acid SCHEMBL27846617 | 0.75 | NTRK1 (0.50) | CDC7TACR1ALDH1A1MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090163471-A1 | Tropane compounds | EXELIXIS, INC. | 2009-06-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163471-A1 | Tropane compounds | ADRA1B, ADRA2B, ADRB2 | KMO 3871/4885CDC7 4431/4885CCNE1 395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.