Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | RBP4 | P02753 | 2/20 | 0.50 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4299301 | 0.95 | MAPT (0.59) | MAPTHRH4MEN1KMT2AKDM4E | |
| SCHEMBL14372216 | 0.83 | MEN1 (0.57) | MAPTHRH4MEN1KMT2AKDM4E | |
| SCHEMBL4306582 | 0.82 | MAPT (0.73) | MAPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL5462589 | 0.82 | HRH4 (0.54) | MAPTHRH4MEN1KMT2AKDM4E | |
| SCHEMBL4299291 | 0.79 | KDM4E (0.67) | MAPTMEN1KMT2AKDM4EPOLB | |
| SCHEMBL10691992 | 0.78 | MAPT (0.49) | MAPTHRH4MEN1KMT2AKDM4E | |
| SCHEMBL4301167 | 0.78 | MAPT (0.67) | MAPTKDM4ELMNARBP4TDP1 | |
| SCHEMBL13234926 | 0.77 | LMNA (0.67) | MAPTMEN1KMT2AKDM4EPOLB | |
| SCHEMBL4224069 | 0.77 | MAPT (0.50) | MAPTPOLBLMNAKCNMA1SMN1; SMN2 | |
| SCHEMBL11055777 | 0.76 | MAPT (0.47) | MAPTHRH4MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090118303-A1 | SEROTONIN 5-HT3 RECEPTOR AGONIST | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2009-05-07 | — | — | US | disclosed |
| US-7485646-B2 | Serotonin 5-HT3 receptor agonist | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2009-02-03 | — | — | US | disclosed |
| US-20070265277-A1 | Serotonin 5-Ht3 Receptor Agonist | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2007-11-15 | — | — | US | disclosed |
| CN-101039927-A | 5-hydroxytryptamine 5-HT 3 receptor agonists | RES FOUND ITSUU LAB (JP) | 2007-09-19 | — | — | CN | disclosed |
| EP-1798227-A1 | SEROTONIN 5-HT3 RECEPTOR AGONIST | Research Foundation Itsuu Laboratory (JP) | 2007-06-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118303-A1 | SEROTONIN 5-HT3 RECEPTOR AGONIST | HTR3A, HTR7, HTR1A | MAPT 4268/4885HRH4 90/4885MEN1 2589/4885 |
| US-20070265277-A1 | Serotonin 5-Ht3 Receptor Agonist | HTR3A, HTR7, HTR1A | MAPT 4268/4885HRH4 90/4885MEN1 2589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.