Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4305020 | 0.85 | LMNA (0.46) | LMNAMAPTMEN1CASP3KMT2A | |
| SCHEMBL4305907 | 0.85 | LMNA (0.38) | LMNAMAPTALDH1A1KDM4EERN1 | |
| SCHEMBL4308531 | 0.84 | LMNA (0.43) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4306380 | 0.83 | CYP1A2 (0.43) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4306412 | 0.82 | KMT2A (0.42) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4306435 | 0.79 | CYP1A2 (0.41) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4302800 | 0.78 | CDYL2 (0.49) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4301396 | 0.77 | KMT2A (0.43) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL4304995 | 0.77 | CYP1A2 (0.43) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4303399 | 0.75 | LMNA (0.37) | LMNAMAPTMEN1CASP3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009130231-A1 | PYRROLO [1, 2-A] PYRAZINE DERIVATIVES AS VASOPRESSIN VIB RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2009-10-29 | — | — | WO | disclosed |
| WO-2009130231-A1 | PYRROLO [1, 2-A] PYRAZINE DERIVATIVES AS VASOPRESSIN VIB RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2009-10-29 | — | — | WO | disclosed |