Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27617903 | 0.99 | FDPS (0.36) | FDPSHRH3LMNAALDH1A1NPC1 | |
| Pyridine SCHEMBL4314632 | 0.74 | SIGMAR1 (0.34) | HTR6 | |
| SCHEMBL8861716 | 0.73 | HTR2A (0.44) | LMNAHRH1HTR6TAAR1CYP1A2 | |
| Hydrochloric Acid SCHEMBL27617901 | 0.72 | L3MBTL1 (0.33) | FDPSALDH1A1NPC1RAB9ACYP1A2 | |
| SCHEMBL8831405 | 0.71 | HTR2A (0.34) | LMNAHRH1HTR6SMN1; SMN2MEN1 | |
| SCHEMBL8831509 | 0.71 | RET (0.41) | LMNAHRH1HTR6SMN1; SMN2MEN1 | |
| SCHEMBL6754873 | 0.71 | HTR6 (0.51) | HRH3LMNAALDH1A1HRH1HTR6 | |
| SCHEMBL1452608 | 0.70 | HTR6 (0.41) | LMNAHRH1HTR6SMN1; SMN2MEN1 | |
| SCHEMBL1030004 | 0.70 | HTR2A (0.38) | LMNAHRH1HTR6SMN1; SMN2MEN1 | |
| SCHEMBL30034828 | 0.70 | SIGMAR1 (0.35) | LMNAHRH1HTR6SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541481-B2 | Monocyclopentadienyl complex | BASELL POLYOLEFIN GMBH (DE) | 2009-06-02 | — | — | US | disclosed |
| US-20070155918-A1 | Monocyclopentadienyl complex | BASELL POLYOLEFINE GMBH (DE) | 2007-07-05 | — | — | US | disclosed |
| US-20060089253-A1 | Monocyclopentadienyl complexes | BASELL POLYOLEFINE GMBH (DE) | 2006-04-27 | — | — | US | disclosed |
| EP-1534724-B1 | MONOCYCLOPENTADIENYL COMPLEXES | BASELL POLYOLEFINE GMBH (DE) | 2006-03-08 | — | — | EP | disclosed |
| EP-1534724-A2 | MONOCYCLOPENTADIENYL COMPLEXES | Basell Polyolefine GmbH (DE) | 2005-06-01 | — | — | EP | disclosed |
| WO-2004020479-A2 | MONOCYCLOPENTADIENYL COMPLEXES | BASELL POLYOLEFINE GMBH (DE) | 2004-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155918-A1 | Monocyclopentadienyl complex | COASY, PCBP1, ORC3 | FDPS 117/4885HRH3 4197/4885LMNA 3188/4885 |
| US-20060089253-A1 | Monocyclopentadienyl complexes | COASY, PCBP1, ORC3 | FDPS 63/4885HRH3 3706/4885LMNA 3042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.