Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 2/20 | 0.39 |
| ▸ | GUSB | P08236 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11628989 | 0.98 | ACHE (0.45) | ACHEALDH1A1GAAMAPTRAB9A | |
| SCHEMBL9306986 | 0.79 | ACHE (0.43) | ACHEALDH1A1GAAMAPTRAB9A | |
| SCHEMBL4612577 | 0.79 | PARP1 (0.50) | ACHEALDH1A1GAAMAPTRAB9A | |
| SCHEMBL21708401 | 0.79 | ALDH1A1 (0.48) | ACHEALDH1A1GAAMAPTRAB9A | |
| SCHEMBL9305473 | 0.79 | ACHE (0.43) | ACHEALDH1A1GAAMAPTRAB9A | |
| SCHEMBL6139628 | 0.79 | DAO (0.43) | ALDH1A1GAAMAPTRAB9AKMT2A | |
| SCHEMBL8956222 | 0.79 | ACHE (0.34) | ACHEALDH1A1GAAMAPTRAB9A | |
| SCHEMBL9533110 | 0.76 | TDP1 (0.41) | ACHEALDH1A1GAAMAPTRAB9A | |
| SCHEMBL6650617 | 0.75 | CDK9 (0.46) | ALDH1A1GAAMAPTRAB9AKMT2A | |
| SCHEMBL7863162 | 0.75 | ALDH1A1 (0.47) | ALDH1A1MAPTRAB9AKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114163647-B | Biomass polybenzimidazole epoxy flame-retardant curing agent and preparation method and application thereof | 厦门大学 | 2022-08-12 | — | — | CN | claimed |
| CN-114163647-A | Biomass polybenzimidazole epoxy flame-retardant curing agent and preparation method and application thereof | 厦门大学 | 2022-03-11 | — | — | CN | claimed |
| EP-1428510-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| US-4131467-A | 4,7-Dihydroxybenzimidazole hydrobromide as antifogger | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-12-26 | — | — | US | claimed |
| CN-118406235-A | High-temperature-resistant polyarylsulfone resin and preparation method thereof | 吉林大学 | 2024-07-30 | — | — | CN | disclosed |
| CN-114163647-B | Biomass polybenzimidazole epoxy flame-retardant curing agent and preparation method and application thereof | 厦门大学 | 2022-08-12 | — | — | CN | disclosed |
| CN-114163647-A | Biomass polybenzimidazole epoxy flame-retardant curing agent and preparation method and application thereof | 厦门大学 | 2022-03-11 | — | — | CN | disclosed |
| US-7547756-B2 | Benzimidazole-containing sulfonated polyethersulfones | GENERAL ELECTRIC COMPANY (US) | 2009-06-16 | — | — | US | disclosed |
| US-20070100131-A1 | Benzimidazole-containing sulfonated polyethersulfones | GENERAL ELECTRIC COMPANY | 2007-05-03 | — | — | US | disclosed |
| EP-1428510-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | disclosed |
| US-6455507-B1 | E.G., 2-BROMO-5,6-DICHLORO-1-BETA-D-RIBOPYRANOSYL-1H-BENZIMIDAZOLE; VIRICIDES, ESPECIALLY INFECTIONS OF HERPES AND CYTOMEGALO VIRUSES | SMITHKLINE BEECHAM CORPORATION | 2002-09-24 | — | — | US | disclosed |
| US-20020094963-A1 | BENZIMIDAZOLE DERIVATIVES | GLAXO WELLCOME INC. | 2002-07-18 | — | — | US | disclosed |
| EP-0994890-A2 | BENZIMIDAZOLE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2000-04-26 | — | — | EP | disclosed |
| WO-1998056761-A2 | BENZIMIDAZOLE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1998-12-17 | — | — | WO | disclosed |
| US-5194433-A | Improved effectiveness against resistant bacteria | BRISTOL-MYERS SQUIBB COMPANY (US) | 1993-03-16 | — | — | US | disclosed |
| EP-0287806-B1 | RUBBER COMPOSITIONS MODIFIED WITH HYDROXY-BENZIMIDAZOLE OXIDES | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1992-10-14 | — | — | EP | disclosed |
| EP-0485808-A2 | Antibiotic C-3 catechol-substituted cephalosporin compounds, compositions and use thereof | Bristol-Myers Squibb Company (US) | 1992-05-20 | — | — | EP | disclosed |
| EP-0287806-A1 | Rubber compositions modified with hydroxy-benzimidazole oxides | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1988-10-26 | — | — | EP | disclosed |
| US-4131467-A | 4,7-Dihydroxybenzimidazole hydrobromide as antifogger | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020094963-A1 | BENZIMIDAZOLE DERIVATIVES | ZC3HAV1, BRPF3, BRD3 | ACHE 3737/4885ALDH1A1 709/4885GAA 235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.