Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 1/20 | 0.30 |
| ▸ | FNTB | P49356 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL432327 | 1.00 | NAMPT (0.35) | NAMPTADRA1ANOD1ALDH1A1MAPT | |
| SCHEMBL30980846 | 0.81 | EPHX1 (0.41) | NOD1MAPTFNTAFNTB | |
| SCHEMBL30980900 | 0.81 | EPHX1 (0.41) | NOD1MAPTFNTAFNTB | |
| SCHEMBL21403573 | 0.78 | ALDH1A1 (0.43) | ALDH1A1MAPTPTGS1MEN1KMT2A | |
| SCHEMBL31196416 | 0.77 | ALOX15 (0.38) | NOD1ALDH1A1MAPTPTGS1MAPK1 | |
| SCHEMBL30597580 | 0.75 | FAAH (0.40) | NOD1ALDH1A1MAPTPTGS1FAAH | |
| SCHEMBL17130499 | 0.73 | FAAH (0.46) | NAMPTADRA1ALMNAFAAHMEN1 | |
| SCHEMBL8053874 | 0.70 | MMP3 (0.41) | ADRA1ALMNAFAAHMEN1MAPK1 | |
| SCHEMBL6159056 | 0.70 | HDAC3 (0.55) | NAMPTLMNAFAAHMEN1MAPK1 | |
| SCHEMBL5909431 | 0.70 | HDAC3 (0.55) | NAMPTLMNAFAAHMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065367-A1 | Radioactively Labeled Substance | NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY (JP) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065367-A1 | Radioactively Labeled Substance | KIT, ABCG2, TK1 | NAMPT 3760/4885ADRA1A 1844/4885NOD1 4788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.