Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2809911 | 0.86 | TSHR (0.34) | KDM4EALOX15TSHRALDH1A1 | |
| SCHEMBL8848573 | 0.84 | KDM4E (0.36) | KDM4EKMT2AMEN1MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL22575357 | 0.82 | KDM4E (0.35) | KDM4EKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL15901082 | 0.80 | KDM4E (0.34) | KDM4E | |
| SCHEMBL6567233 | 0.80 | MAPT (0.35) | KDM4EKMT2AALOX15MEN1CYP3A4 | |
| SCHEMBL3037685 | 0.80 | MAPT (0.35) | KDM4EKMT2AALOX15MEN1CYP3A4 | |
| Hydrochloric Acid SCHEMBL22771839 | 0.78 | KDM4E (0.33) | KDM4E | |
| Hydrochloric Acid SCHEMBL28898248 | 0.78 | KDM4E (0.33) | KDM4E | |
| SCHEMBL2141526 | 0.76 | — | — | |
| SCHEMBL22693092 | 0.76 | KDM4E (0.32) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080015121-A1 | Compositions, methods and uses for sterically hindered quaternary ammonium compounds | BAKER HUGHES INCORPORATED (US) | 2008-01-17 | — | — | US | claimed |
| WO-2008008697-A2 | COMPOSITIONS, METHODS AND USES FOR STERICALLY-HINDERED QUATERNARY AMMONIUM COMPOUNDS | BAKER HUGHES INCORPORATED (US) | 2008-01-17 | — | — | WO | claimed |
| US-20140370279-A1 | METHODS OF COATING A LOW SURFACE ENERGY SUBSTRATE | NOVEL POLYMER SOLUTIONS LIMITED (GB) | 2014-12-18 | — | — | US | disclosed |
| EP-2601047-B1 | METHODS OF COATING A LOW SURFACE ENERGY SUBSTRATE | SYNTOR FINE CHEMICALS LTD (GB) | 2014-11-26 | — | — | EP | disclosed |
| US-8580990-B2 | Gold catalyzed hydroamination of alkynes and allenes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-11-12 | — | — | US | disclosed |
| US-8580990-B2 | Gold catalyzed hydroamination of alkynes and allenes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-11-12 | — | — | US | disclosed |
| US-8580990-B2 | Gold catalyzed hydroamination of alkynes and allenes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-11-12 | — | — | US | disclosed |
| US-8334412-B2 | Process for preparing 3-(methylthio)propanal | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-12-18 | — | — | US | disclosed |
| US-8173845-B2 | Process for producing 3-methylthiopropanal | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-05-08 | — | — | US | disclosed |
| US-20120022295-A1 | PROCESS FOR PREPARING 3-(METHYLTHIO)PROPANAL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-01-26 | — | — | US | disclosed |
| EP-2239252-B1 | Process for producing 3-methylthiopropanal | SUMITOMO CHEMICAL CO (JP) | 2011-10-19 | — | — | EP | disclosed |
| US-20110166349-A1 | GOLD CATALYZED HYDROAMINATION OF ALKYNES AND ALLENES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-07-07 | — | — | US | disclosed |
| US-20110166349-A1 | GOLD CATALYZED HYDROAMINATION OF ALKYNES AND ALLENES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-07-07 | — | — | US | disclosed |
| EP-2239252-A1 | Process for producing 3-methylthiopropanal | Sumitomo Chemical Company, Limited (JP) | 2010-10-13 | — | — | EP | disclosed |
| US-20100256419-A1 | PROCESS FOR PRODUCING 3-METHYLTHIOPROPANAL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-10-07 | — | — | US | disclosed |
| WO-2009137810-A2 | GOLD CATALYZED HYDROAMINATION OF ALKYNES AND ALLENES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-11-12 | — | — | WO | disclosed |
| WO-2009137810-A2 | GOLD CATALYZED HYDROAMINATION OF ALKYNES AND ALLENES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-11-12 | — | — | WO | disclosed |
| US-20080293597-A1 | METHOD FOR INHIBITING HYDRATE FORMATION | BAKER HUGHES INCORPORATED (US) | 2008-11-27 | — | — | US | disclosed |
| US-20080015121-A1 | Compositions, methods and uses for sterically hindered quaternary ammonium compounds | BAKER HUGHES INCORPORATED (US) | 2008-01-17 | — | — | US | disclosed |
| WO-2008008697-A2 | COMPOSITIONS, METHODS AND USES FOR STERICALLY-HINDERED QUATERNARY AMMONIUM COMPOUNDS | BAKER HUGHES INCORPORATED (US) | 2008-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080015121-A1 | Compositions, methods and uses for sterically hindered quaternary ammonium compounds | HDHD5, DHX29, KAT7 | KDM4E 3291/4885KMT2A 1584/4885ALOX15 3954/4885 |
| US-20100256419-A1 | PROCESS FOR PRODUCING 3-METHYLTHIOPROPANAL | MGMT, TPMT, PTMA | KDM4E 4370/4885KMT2A 2862/4885ALOX15 2231/4885 |
| US-20080293597-A1 | METHOD FOR INHIBITING HYDRATE FORMATION | HDHD5, DHX29, DHX9 | KDM4E 3503/4885KMT2A 1577/4885ALOX15 3644/4885 |
| US-20120022295-A1 | PROCESS FOR PREPARING 3-(METHYLTHIO)PROPANAL | PTMA, TMT1A, MGMT | KDM4E 4468/4885KMT2A 2036/4885ALOX15 965/4885 |
| US-20110166349-A1 | GOLD CATALYZED HYDROAMINATION OF ALKYNES AND ALLENES | AOC3, AOC2, AOC1 | KDM4E 982/4885KMT2A 984/4885ALOX15 969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.