Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4452789 | 0.81 | PKM (0.50) | PKMSLC6A2SLC6A4SLC6A3KDM4E | |
| SCHEMBL4316512 | 0.72 | SLC6A4 (0.52) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4462738 | 0.69 | MAOA (0.38) | PKMSLC6A4KDM4EBCHE | |
| SCHEMBL4328800 | 0.69 | SLC6A4 (0.38) | PKMSLC6A2SLC6A4SLC6A3KDM4E | |
| SCHEMBL4459145 | 0.69 | PKM (0.43) | PKMLMNASLC6A4KDM4EALDH1A1 | |
| SCHEMBL4333697 | 0.68 | MAOA (0.40) | PKMMAPTSLC6A4KDM4EALDH1A1 | |
| SCHEMBL4338581 | 0.68 | MAOA (0.38) | PKMSLC6A4KDM4E | |
| SCHEMBL4323108 | 0.67 | SLC6A2 (0.48) | MAPTLMNASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4458919 | 0.67 | SLC6A2 (0.48) | MAPTLMNASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4325036 | 0.67 | SLC6A2 (0.50) | DRD1SLC6A2SLC6A4SLC6A3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118765-A2 | NOVEL MONOAMINE RE-UPTAKE INHIBITOR | PANACEA BIOTEC LIMITED (GB) | 2009-10-01 | — | — | WO | claimed |
| WO-2009118765-A2 | NOVEL MONOAMINE RE-UPTAKE INHIBITOR | PANACEA BIOTEC LIMITED (GB) | 2009-10-01 | — | — | WO | disclosed |