Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4328800 | 0.87 | SLC6A4 (0.38) | PKMKDM4ESLC6A4MAOAMAOB | |
| SCHEMBL4462738 | 0.87 | MAOA (0.38) | PKMKDM4ESLC6A4MAOAMAOB | |
| SCHEMBL4459145 | 0.87 | PKM (0.43) | PKMKDM4ESLC6A4MAOAMAOB | |
| SCHEMBL4338581 | 0.86 | MAOA (0.38) | PKMKDM4ESLC6A4MAOAMAOB | |
| SCHEMBL4333697 | 0.86 | MAOA (0.40) | PKMKDM4ESLC6A4MAOAMAOB | |
| SCHEMBL4320735 | 0.84 | MAOA (0.39) | PKMKDM4ESLC6A4MAOAMAOB | |
| SCHEMBL4316512 | 0.82 | SLC6A4 (0.52) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL4317443 | 0.81 | PKM (0.39) | PKMKDM4ESLC6A4SLC6A2SLC6A3 | |
| SCHEMBL4331887 | 0.81 | PKM (0.45) | PKMKDM4E | |
| SCHEMBL4325036 | 0.77 | SLC6A2 (0.50) | SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118765-A2 | NOVEL MONOAMINE RE-UPTAKE INHIBITOR | PANACEA BIOTEC LIMITED (GB) | 2009-10-01 | — | — | WO | disclosed |