Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 12/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4323016 | 0.92 | MEN1 (0.36) | MEN1KMT2AATMLMNANPSR1 | |
| SCHEMBL4325137 | 0.91 | MEN1 (0.37) | MEN1KMT2AATMLMNANPSR1 | |
| SCHEMBL4318374 | 0.89 | OPRL1 (0.36) | OPRL1OPRM1DRD2HTR1AHTR7 | |
| SCHEMBL4329857 | 0.88 | HTR1A (0.33) | OPRL1OPRM1DRD2HTR1AHTR7 | |
| SCHEMBL4334663 | 0.88 | HTR1A (0.33) | OPRL1OPRM1DRD2HTR1AHTR7 | |
| SCHEMBL4318607 | 0.86 | OPRL1 (0.34) | OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL4321304 | 0.82 | MEN1 (0.35) | MEN1KMT2AATMLMNANPSR1 | |
| SCHEMBL4322971 | 0.81 | LMNA (0.38) | MEN1KMT2AATMLMNANPSR1 | |
| SCHEMBL4328886 | 0.81 | ALDH1A1 (0.36) | LMNANPSR1OPRL1OPRM1DRD2 | |
| SCHEMBL4335933 | 0.79 | OPRM1 (0.35) | OPRL1OPRM1OPRD1OPRK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069340-A1 | Pyrazolone Compounds As Metabotropic Glutamate Receptor Agonists For The Treatment Of Neurological And Psychiatric Disorders | ASTRAZENECA AB (SE) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069340-A1 | Pyrazolone Compounds As Metabotropic Glutamate Receptor Agonists For The Treatment Of Neurological And Psychiatric Disorders | GRIN1, GRM1, GRIN3A | MEN1 3300/4885KMT2A 2407/4885ATM 1561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.