Sugi Predict

Sugi Predict / Compounds / SCHEMBL4322090

SCHEMBL4322090

SCHEMBL4322090

O=C1c2ccc(F)cc2-c2cc(F)ccc21

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 1/20 0.52
▸ CA2 P00918 1/20 0.52
▸ CA7 P43166 1/20 0.52
▸ CA9 Q16790 1/20 0.52
▸ PTPN1 P18031 1/20 0.46
▸ USP8 P40818 1/20 0.44
▸ USP7 Q93009 1/20 0.44
▸ USP47 Q96K76 1/20 0.44
▸ MAOB P27338 2/20 0.44
▸ ESR1 P03372 1/20 0.44
▸ MAOA P21397 1/20 0.44
▸ UGT1A1 P22309 1/20 0.44
▸ ESR2 Q92731 1/20 0.44
▸ MEN1 O00255 1/20 0.43
▸ CDC25B P30305 1/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ PARK7 Q99497 1/20 0.42
▸ ALDH1A1 P00352 3/20 0.42
▸ CYP3A4 P08684 2/20 0.42
▸ CYP1A2 P05177 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9811010 0.95 CA1 (0.48) CA1CA2CA7CA9PTPN1
SCHEMBL13487415 0.94 CA1 (0.52) CA1CA2CA7CA9PTPN1
SCHEMBL9328908 0.94 CA1 (0.52) CA1CA2CA7CA9PTPN1
SCHEMBL563010 0.91 MEN1 (0.55) PTPN1USP8USP7MAOBMAOA
SCHEMBL7432075 0.89 CA1 (0.52) CA1CA2CA7CA9PTPN1
SCHEMBL30479662 0.89 CA1 (0.52) CA1CA2CA7CA9PTPN1
SCHEMBL3894758 0.87 MEN1 (0.57) CA1CA2CA7CA9PTPN1
SCHEMBL181722 0.85 PTPRC (0.55) PTPN1USP8USP7MAOBMAOA
SCHEMBL13487417 0.85 PTPRC (0.59) PTPN1MAOAMEN1CDC25BKMT2A
SCHEMBL29390818 0.85 PTPRC (0.55) PTPN1USP8USP7MAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250382270-A1 3-DIARYLMETHYLENES AND USES THEREOF ATUX ISKAY LLC (US) 2025-12-18 — — US disclosed
US-20250340514-A1 3-DIARYLMETHYLENES AND USES THEREOF ATUX ISKAY LLC (US) 2025-11-06 — — US disclosed
US-12398103-B2 3-diarylmethylenes and uses thereof ATUX ISKAY LLC (US) 2025-08-26 — — US disclosed
CN-113795476-B Compound having fluorene skeleton and method for producing same 帝人株式会社 2024-04-09 — — CN disclosed
CN-111465589-B Compound having fluorene skeleton and method for producing same 帝人株式会社 2024-01-05 — — CN disclosed
US-11655264-B2 Metallocene compounds, and preparation and use thereof for synthesis of poly-alpha-olefins as lubricating base oil APALENE TECHNOLOGY CO., LTD. (HANGZHOU) (CN) 2023-05-23 — — US disclosed
US-20230146127-A1 3-DIARYLMETHYLENES AND USES THEREOF ATUX ISKAY LLC 2023-05-11 — — US disclosed
US-20230146127-A1 3-DIARYLMETHYLENES AND USES THEREOF ATUX ISKAY LLC 2023-05-11 — — US disclosed
CN-115956005-A Fluorene derivative and method for producing same 帝人株式会社 2023-04-11 — — CN disclosed
EP-4121031-A1 3-DIARYLMETHYLENES AND USES THEREOF Atux Iskay LLC (US) 2023-01-25 — — EP disclosed
US-20010037037-A1 Oximesulfonic acid esters and the use thereof as latent sulfonic acids CIBA SPEICIALTY CHEMICALS CORP. 2001-11-01 — — US disclosed
US-6017675-A POLYMERIZATION CATALYST CIBA SPECIALTY CHEMIALS CORPORATION (US) 2000-01-25 — — US disclosed
EP-0581058-A1 Polyaryl ether films HOECHST AKTIENGESELLSCHAFT (DE) 1994-02-02 — — EP disclosed
US-5194561-A PROCESS FOR THE PREPARATION OF AN AROMATIC POLYETHER IN THE PRESENCE OF FINELY DIVIDED CONDENSATION AUXILIARIES HOECHST AKTIENGESELLSCHAFT (DE) 1993-03-16 — — US disclosed
US-5081214-A Mixture of Sodium Carbonate and Sodium Bicarbonate HOECHST AKTIENGESELLSCHAFT (DE) 1992-01-14 — — US disclosed
EP-0412498-A2 Process for preparation of an aromatic polyether HOECHST AKTIENGESELLSCHAFT (DE) 1991-02-13 — — EP disclosed
EP-0412499-A2 Process for the preparation of an aromatic polyether in the presence of finely dispersed condensation agents HOECHST AKTIENGESELLSCHAFT (DE) 1991-02-13 — — EP disclosed
US-4636557-A Process for the preparation of aromatic polyethers with mixture of carbonate catalysts HOECHST AKTIENGESELLSCHAFT (DE) 1987-01-13 — — US disclosed
EP-0143407-B1 PROCESS FOR PREPARING AROMATIC POLYETHERS HOECHST AKTIENGESELLSCHAFT (DE) 1986-11-12 — — EP disclosed
EP-0143407-A2 Process for preparing aromatic polyethers HOECHST AKTIENGESELLSCHAFT (DE) 1985-06-05 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250382270-A1 3-DIARYLMETHYLENES AND USES THEREOF MYC, MYCBP, FOXO1 CA1 4607/4885CA2 4322/4885CA7 4384/4885
US-12398103-B2 3-diarylmethylenes and uses thereof MYC, MYCBP, FOXO1 CA1 4607/4885CA2 4322/4885CA7 4384/4885
US-20250340514-A1 3-DIARYLMETHYLENES AND USES THEREOF MYC, MYCBP, FOXO1 CA1 4607/4885CA2 4322/4885CA7 4384/4885
US-20230146127-A1 3-DIARYLMETHYLENES AND USES THEREOF MYC, MYCBP, FOXO1 CA1 4607/4885CA2 4322/4885CA7 4384/4885
US-20010037037-A1 Oximesulfonic acid esters and the use thereof as latent sulfonic acids QSOX1, HAO2, PAH CA1 442/4885CA2 220/4885CA7 159/4885
US-11655264-B2 Metallocene compounds, and preparation and use thereof for synthesis of poly-alpha-olefins as lubricating base oil POLM, POLA1, POLD1 CA1 3273/4885CA2 4716/4885CA7 3850/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.