SCHEMBL4323348

SCHEMBL4323348

O=C(Cl)Cc1ccc(O)c(O)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.67
MAPT P10636 3/20 0.67
HIF1A Q16665 3/20 0.67
HSD17B10 Q99714 3/20 0.67
TDP1 Q9NUW8 3/20 0.67
GAA P10253 2/20 0.67
APEX1 P27695 2/20 0.67
THPO P40225 2/20 0.67
RGS12 O14924 1/20 0.67
LMNA P02545 1/20 0.67
POLB P06746 1/20 0.67
HPGD P15428 1/20 0.67
TSHR P16473 1/20 0.67
NFKB1 P19838 1/20 0.67
BLM P54132 1/20 0.67
GNAI1 P63096 1/20 0.67
PMP22 Q01453 1/20 0.67
CA2 P00918 2/20 0.54
CA1 P00915 1/20 0.54
CA4 P22748 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26722695 0.83 KDM4E (0.67) KDM4EMAPTHIF1AHSD17B10TDP1
SCHEMBL22982989 0.82 KDM4E (0.72) KDM4EMAPTHIF1AHSD17B10TDP1
SCHEMBL31618868 0.82 KDM4E (0.72) KDM4EMAPTHIF1AHSD17B10TDP1
SCHEMBL23276708 0.82 ESR1 (0.59) KDM4EMAPTHIF1AHSD17B10TDP1
3,4-Dihydroxyphenylacetic Acid SCHEMBL36348 0.80 GAA (1.00) KDM4EMAPTHIF1AHSD17B10TDP1
3,4-Dihydroxyphenylacetic Acid SCHEMBL29382155 0.80 GAA (1.00) KDM4EMAPTHIF1AHSD17B10TDP1
SCHEMBL22079250 0.79 IAPP (0.62) KDM4EMAPTHIF1AHSD17B10TDP1
SCHEMBL10595930 0.78 KDM4E (0.67) KDM4EMAPTHIF1AHSD17B10TDP1
3,4-Dihydroxyphenylacetic Acid SCHEMBL8214149 0.78 KDM4E (0.67) KDM4EMAPTHIF1AHSD17B10TDP1
3,4-Dihydroxyphenylacetic Acid SCHEMBL8214151 0.78 GAA (0.96) KDM4EMAPTHIF1AHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12358934-B2 Phosphorus-containing compound and preparation method and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2025-07-15 US claimed
CN-117772287-A Graphene-based heterogeneous catalyst and preparation method and application thereof 山东海科创新研究院有限公司 2024-03-29 CN claimed
US-20220289771-A1 Phosphorus-containing Compound and Preparation Method and Use Thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2022-09-15 US claimed
EP-4050015-A1 PHOSPHORUS-CONTAINING COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF China Petroleum & Chemical Corporation (CN) 2022-08-31 EP claimed
CN-112760158-B Gasoline engine lubricating oil composition and preparation method thereof 中国石油化工股份有限公司 2022-07-15 CN claimed
CN-112760156-B Calcium-based lubricating grease and preparation method thereof 中国石油化工股份有限公司 2022-07-15 CN claimed
CN-112760161-B Anhydrous calcium-based lubricating grease and preparation method thereof 中国石油化工股份有限公司 2022-07-15 CN claimed
CN-112760157-B Composite lithium-based lubricating grease and preparation method thereof 中国石油化工股份有限公司 2022-07-12 CN claimed
CN-112760155-A Lubricating oil composition for diesel engine and preparation method thereof 中国石油化工股份有限公司 2021-05-07 CN claimed
CN-112760156-A Calcium-based lubricating grease and preparation method thereof 中国石油化工股份有限公司 2021-05-07 CN claimed
CN-112760152-A Lithium-based lubricating grease and preparation method thereof 中国石油化工股份有限公司 2021-05-07 CN claimed
CN-112760154-A Natural gas engine lubricating oil composition and preparation method thereof 中国石油化工股份有限公司 2021-05-07 CN claimed
CN-112760158-A Gasoline engine lubricating oil composition and preparation method thereof 中国石油化工股份有限公司 2021-05-07 CN claimed
CN-112760161-A Anhydrous calcium-based lubricating grease and preparation method thereof 中国石油化工股份有限公司 2021-05-07 CN claimed
CN-112760157-A Composite lithium-based lubricating grease and preparation method thereof 中国石油化工股份有限公司 2021-05-07 CN claimed
CN-112759610-A Phosphorus-containing compound and preparation method and application thereof 中国石油化工股份有限公司 2021-05-07 CN claimed
WO-2021078137-A1 PHOSPHORUS-CONTAINING COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF 中国石油化工股份有限公司 2021-04-29 WO claimed
US-12358934-B2 Phosphorus-containing compound and preparation method and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2025-07-15 US disclosed
EP-0066373-B1 BETA-LACTAM DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM BEECHAM GROUP PLC (GB) 1985-03-20 EP disclosed
EP-0066373-A1 Beta-lactam derivatives, a process for their preparation and compositions containing them BEECHAM GROUP PLC (GB) 1982-12-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12358934-B2 Phosphorus-containing compound and preparation method and use thereof PHOSPHO1, SOST, PLTP KDM4E 4232/4885MAPT 4178/4885HIF1A 2448/4885
US-20220289771-A1 Phosphorus-containing Compound and Preparation Method and Use Thereof PHOSPHO1, SOST, PLTP KDM4E 4232/4885MAPT 4178/4885HIF1A 2448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.