Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4324689 | 1.00 | ALDH1A1 (0.47) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL27746963 | 0.89 | ALDH1A1 (0.44) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL1033690 | 0.82 | MAPT (0.49) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL1033691 | 0.82 | MAPT (0.49) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL28385269 | 0.81 | MAPT (0.51) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL6169631 | 0.78 | MAPT (0.48) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL18802206 | 0.76 | NFE2L2 (0.50) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL6172600 | 0.76 | PTGS2 (0.48) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL6172610 | 0.76 | PTGS2 (0.48) | ALDH1A1KMT2AMAPTMEN1KDM4E | |
| SCHEMBL67953 | 0.75 | PTGS2 (0.47) | KMT2AMAPTMEN1PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014652-B1 | ACTIVATING AGENT FOR PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR | NIPPON CHEMIPHAR CO (JP) | 2014-08-06 | — | — | EP | disclosed |
| US-20130217734-A1 | ACTIVATING AGENT FOR PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA | NIPPON CHEMIPHAR CO., LTD. (JP) | 2013-08-22 | — | — | US | disclosed |
| US-8404726-B2 | Activating agent for peroxisome proliferator activated receptor δ | NIPPON CHEMIPHAR CO. LTD. (JP) | 2013-03-26 | — | — | US | disclosed |
| US-20090298896-A1 | ACTIVATING AGENT FOR PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA | NIPPON CHEMIPHAR CO. LTD | 2009-12-03 | — | — | US | disclosed |
| EP-2014652-A1 | ACTIVATING AGENT FOR PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR | Nippon Chemiphar Co., Ltd. (JP) | 2009-01-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298896-A1 | ACTIVATING AGENT FOR PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA | PPARA, PPARG, PPARD | ALDH1A1 534/4885KMT2A 1816/4885MAPT 4812/4885 |
| US-20130217734-A1 | ACTIVATING AGENT FOR PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA | PPARA, PPARG, PPARD | ALDH1A1 534/4885KMT2A 1816/4885MAPT 4812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.