Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | EZH2 | Q15910 | 5/20 | 0.41 |
| ▸ | RORC | P51449 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.38 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13578169 | 0.95 | L3MBTL1 (0.47) | L3MBTL1EZH2KMT2APOLBMAP2K3 | |
| Trifluoroacetic Acid SCHEMBL4327668 | 0.91 | MAP2K3 (0.48) | L3MBTL1EZH2RORCKMT2APPARG | |
| Trifluoroacetic Acid SCHEMBL4333038 | 0.86 | KMT2A (0.48) | L3MBTL1EZH2RORCKMT2APPARG | |
| Trifluoroacetic Acid SCHEMBL4331249 | 0.85 | GABRA5 (0.40) | RORCKMT2APPARGHTR4KDM4E | |
| Trifluoroacetic Acid SCHEMBL4336494 | 0.84 | RORC (0.44) | RORCPPARGHTR4MAP2K3KDM4E | |
| SCHEMBL13578150 | 0.84 | MAP2K3 (0.55) | L3MBTL1EZH2KMT2APOLBMAP2K3 | |
| Trifluoroacetic Acid SCHEMBL4339706 | 0.84 | RORC (0.42) | RORCPPARGHTR4MAP2K3 | |
| Trifluoroacetic Acid SCHEMBL4339713 | 0.83 | CSNK1D (0.46) | RORCPPARGHTR4 | |
| Trifluoroacetic Acid SCHEMBL4334901 | 0.81 | CNR2 (0.44) | — | |
| SCHEMBL13578163 | 0.79 | KMT2A (0.54) | L3MBTL1EZH2RORCKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325936-A1 | IMIDAZOPYRIDINE ANALOGS AS CB2 RECEPTOR MODULATORS, USEFUL IN THE TREATMENT OF PAIN, RESPIRATORY AND NON-RESPIRATORY DISEASES | MERCK & CO., INC. | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325936-A1 | IMIDAZOPYRIDINE ANALOGS AS CB2 RECEPTOR MODULATORS, USEFUL IN THE TREATMENT OF PAIN, RESPIRATORY AND NON-RESPIRATORY DISEASES | CNR2, CNR1, TRPV1 | L3MBTL1 4825/4885EZH2 3737/4885RORC 135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.