Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13578198 | 0.95 | GABRA5 (0.41) | GABRA5RORCMEN1KMT2AHTR4 | |
| Trifluoroacetic Acid SCHEMBL4325479 | 0.92 | MAP2K3 (0.46) | GABRA5RORCMEN1KMT2AHTR4 | |
| Trifluoroacetic Acid SCHEMBL4333549 | 0.87 | ATM (0.42) | GABRA5RORCMEN1KMT2ANPC1 | |
| Trifluoroacetic Acid SCHEMBL4339713 | 0.87 | CSNK1D (0.46) | GABRA5RORCHTR4CSNK1DCSNK1E | |
| Trifluoroacetic Acid SCHEMBL4321784 | 0.85 | KMT2A (0.42) | GABRA5MEN1KMT2AHTR4NPC1 | |
| SCHEMBL13578151 | 0.85 | MAP2K3 (0.51) | GABRA5HTR4NPC1RAB9AAPAF1 | |
| Trifluoroacetic Acid SCHEMBL4326422 | 0.85 | L3MBTL1 (0.42) | RORCKMT2AHTR4KDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL4339706 | 0.83 | RORC (0.42) | RORCHTR4PPARGCNR1CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL4336494 | 0.82 | RORC (0.44) | RORCHTR4CSNK1DCSNK1EKDM4E | |
| SCHEMBL13578200 | 0.81 | CSNK1D (0.47) | GABRA5RORCHTR4CSNK1DCSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325936-A1 | IMIDAZOPYRIDINE ANALOGS AS CB2 RECEPTOR MODULATORS, USEFUL IN THE TREATMENT OF PAIN, RESPIRATORY AND NON-RESPIRATORY DISEASES | MERCK & CO., INC. | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325936-A1 | IMIDAZOPYRIDINE ANALOGS AS CB2 RECEPTOR MODULATORS, USEFUL IN THE TREATMENT OF PAIN, RESPIRATORY AND NON-RESPIRATORY DISEASES | CNR2, CNR1, TRPV1 | GABRA5 104/4885RORC 135/4885MEN1 4456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.