Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | SLC6A15 | Q9H2J7 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | JAK1 | P23458 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.34 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL433156 | 0.85 | MDM2 (0.42) | HDAC2HRH1SLC6A15PIK3CDGPR119 | |
| SCHEMBL432988 | 0.82 | CACNB4 (0.41) | HDAC2PIK3CD | |
| SCHEMBL433103 | 0.75 | HDAC2 (0.39) | HDAC2HRH1SLC6A15GPR119KIT | |
| SCHEMBL462925 | 0.70 | HDAC2 (0.36) | HDAC2PIK3CDGPR119MEN1KMT2A | |
| SCHEMBL434448 | 0.70 | HDAC2 (0.40) | HDAC2GPR119KIT | |
| SCHEMBL432425 | 0.69 | HDAC2 (0.39) | HDAC2HRH1SLC6A15GPR119KIT | |
| SCHEMBL4191420 | 0.68 | FAAH (0.49) | KITPOLB | |
| SCHEMBL2229068 | 0.68 | RAB9A (0.44) | HDAC2KITPOLBJAK2JAK1 | |
| SCHEMBL29283992 | 0.67 | TDP1 (0.41) | — | |
| SCHEMBL16053741 | 0.67 | ENPP2 (0.46) | HDAC2KITPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012366-A1 | PESTICIDAL 3-(ARYLOXY)AZACYCLOALKANES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-01-26 | — | — | WO | disclosed |