Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 3/20 | 0.64 |
| ▸ | THRB | P10828 | 3/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL967078 | 0.86 | HSD17B10 (0.67) | THRATHRBHSD17B10 | |
| SCHEMBL963847 | 0.84 | THRA (0.67) | THRATHRBHSD17B10 | |
| SCHEMBL9997622 | 0.82 | THRA (0.70) | THRATHRBHSD17B10 | |
| SCHEMBL965453 | 0.82 | THRA (0.70) | THRATHRBHSD17B10 | |
| SCHEMBL28733046 | 0.82 | THRA (0.70) | THRATHRBHSD17B10 | |
| SCHEMBL4185050 | 0.82 | THRA (0.70) | THRATHRBHSD17B10 | |
| SCHEMBL499485 | 0.82 | THRA (0.70) | THRATHRBHSD17B10 | |
| SCHEMBL965858 | 0.82 | THRA (0.70) | THRATHRBHSD17B10 | |
| SCHEMBL8383207 | 0.82 | THRA (0.70) | THRATHRBHSD17B10 | |
| SCHEMBL12457863 | 0.82 | THRA (0.70) | THRATHRBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8748636-B2 | Process for preparing benzofuran derivatives substituted at position 5 | SANOFI (FR) | 2014-06-10 | — | — | US | disclosed |
| US-8748636-B2 | Process for preparing benzofuran derivatives substituted at position 5 | SANOFI (FR) | 2014-06-10 | — | — | US | disclosed |
| US-8748636-B2 | Process for preparing benzofuran derivatives substituted at position 5 | SANOFI (FR) | 2014-06-10 | — | — | US | disclosed |
| US-20130165674-A1 | PROCESS FOR PREPARING BENZOFURAN DERIVATIVES SUBSTITUTED AT POSITION 5 | SANOFI (FR) | 2013-06-27 | — | — | US | disclosed |
| US-20130165674-A1 | PROCESS FOR PREPARING BENZOFURAN DERIVATIVES SUBSTITUTED AT POSITION 5 | SANOFI (FR) | 2013-06-27 | — | — | US | disclosed |
| US-20130165674-A1 | PROCESS FOR PREPARING BENZOFURAN DERIVATIVES SUBSTITUTED AT POSITION 5 | SANOFI (FR) | 2013-06-27 | — | — | US | disclosed |
| EP-2595977-A1 | PROCESS FOR PREPARING BENZOFURAN DERIVATIVES SUBSTITUTED AT POSITION 5 | SANOFI (FR) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012010802-A1 | PROCESS FOR PREPARING BENZOFURAN DERIVATIVES SUBSTITUTED AT POSITION 5 | SANOFI (FR) | 2012-01-26 | — | — | WO | disclosed |
| WO-2012010802-A1 | PROCESS FOR PREPARING BENZOFURAN DERIVATIVES SUBSTITUTED AT POSITION 5 | SANOFI (FR) | 2012-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165674-A1 | PROCESS FOR PREPARING BENZOFURAN DERIVATIVES SUBSTITUTED AT POSITION 5 | DHPS, SDHA, CYP2F1 | THRA 3592/4885THRB 3390/4885HSD17B10 129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.