Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUN | P05412 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | FDPS | P14324 | 2/20 | 0.53 |
| ▸ | APP | P05067 | 3/20 | 0.52 |
| ▸ | TOP2A | P11388 | 1/20 | 0.49 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28100185 | 0.93 | NFKB1 (0.48) | JUNNFKB1KDM4EALDH1A1HPGD | |
| SCHEMBL8937934 | 0.87 | KDM4E (0.75) | JUNNFKB1KDM4EALDH1A1HPGD | |
| SCHEMBL29503043 | 0.87 | KDM4E (0.73) | JUNNFKB1KDM4EALDH1A1HPGD | |
| SCHEMBL1589619 | 0.87 | KDM4E (0.73) | JUNNFKB1KDM4EALDH1A1HPGD | |
| SCHEMBL1589618 | 0.87 | KDM4E (0.73) | JUNNFKB1KDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL8937884 | 0.86 | KDM4E (0.73) | JUNNFKB1KDM4EALDH1A1HPGD | |
| SCHEMBL4128281 | 0.86 | JUN (0.78) | JUNNFKB1KDM4EALDH1A1HPGD | |
| SCHEMBL4121496 | 0.86 | JUN (0.78) | JUNNFKB1KDM4EALDH1A1HPGD | |
| SCHEMBL9553292 | 0.81 | ALDH1A1 (0.66) | JUNNFKB1KDM4EALDH1A1HPGD | |
| SCHEMBL16670596 | 0.81 | NFE2L2 (0.51) | JUNNFKB1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11326178-B2 | P-coumaroyl-CoA:monolignol transferase | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2022-05-10 | — | — | US | disclosed |
| US-10428342-B2 | P-coumaroyl-CoA:monolignol transferase | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2019-10-01 | — | — | US | disclosed |
| EP-3138919-B1 | FERULOYL-COA:MONOLIGNOL-TRANSFERASE | UNIV MICHIGAN STATE (US) | 2018-12-19 | — | — | EP | disclosed |
| US-10059955-B2 | Hibiscus cannabinus feruloyl-CoA:monolignol transferase | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2018-08-28 | — | — | US | disclosed |
| EP-2764096-B1 | HIBISCUS CANNABINUS FERULOYL-COA:MONOLIGNOL TRANSFERASE | UNIV MICHIGAN STATE (US) | 2018-04-04 | — | — | EP | disclosed |
| US-20170218004-A1 | FERULOYL-CoA:MONOLIGNOL TRANSFERASE | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2017-08-03 | — | — | US | disclosed |
| US-20170096675-A1 | HIBISCUS CANNABINUS FERULOYL-COA:MONOLIGNOL TRANSFERASE | UNITED STATES DEPARTMENT OF ENERGY | 2017-04-06 | — | — | US | disclosed |
| EP-3138919-A1 | FERULOYL-CoA:MONOLIGNOL-TRANSFERASE | Board of Trustees of Michigan State University (US) | 2017-03-08 | — | — | EP | disclosed |
| EP-2596103-B1 | FERULOYL-CoA:MONOLIGNOL TRANSFERASE | UNIV MICHIGAN STATE (US) | 2016-12-21 | — | — | EP | disclosed |
| US-9493783-B2 | Hibiscus cannabinus feruloyl-coa:monolignol transferase | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2016-11-15 | — | — | US | disclosed |
| US-20160046955-A1 | p-Coumaroyl-CoA:Monolignol Transferase | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2016-02-18 | — | — | US | disclosed |
| EP-2764096-A1 | HIBISCUS CANNABINUS FERULOYL-COA:MONOLIGNOL TRANSFERASE | Board Of Trustees Of Michigan State University (US) | 2014-08-13 | — | — | EP | disclosed |
| US-20130219547-A1 | FERULOYL-CoA:MONOLIGNOL TRANSFERASE | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2013-08-22 | — | — | US | disclosed |
| US-20130203973-A1 | FERULOYL-CoA:MONOLIGNOL TRANSFERASE | ENERGY, UNITED STATES DEPARTMENT OF | 2013-08-08 | — | — | US | disclosed |
| WO-2013090814-A2 | p-Coumaroyl-CoA:Monolignol Transferase | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2013-06-20 | — | — | WO | disclosed |
| EP-2596104-A1 | FERULOYL-CoA:MONOLIGNOL TRANSFERASE | Board Of Trustees Of Michigan State University (US) | 2013-05-29 | — | — | EP | disclosed |
| EP-2596103-A1 | FERULOYL-CoA:MONOLIGNOL TRANSFERASE | Board Of Trustees Of Michigan State University (US) | 2013-05-29 | — | — | EP | disclosed |
| WO-2013052660-A1 | HIBISCUS CANNABINUS FERULOYL-COA:MONOLIGNOL TRANSFERASE | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2013-04-11 | — | — | WO | disclosed |
| WO-2012012741-A1 | FERULOYL-CoA:MONOLIGNOL TRANSFERASE | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2012-01-26 | — | — | WO | disclosed |
| WO-2012012698-A1 | FERULOYL-CoA:MONOLIGNOL TRANSFERASE | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2012-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130203973-A1 | FERULOYL-CoA:MONOLIGNOL TRANSFERASE | COASY, FDFT1, FER | JUN 2095/4885NFKB1 2470/4885KDM4E 1814/4885 |
| US-20170218004-A1 | FERULOYL-CoA:MONOLIGNOL TRANSFERASE | COASY, FDFT1, FER | JUN 2095/4885NFKB1 2470/4885KDM4E 1814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.