SCHEMBL4328541

SCHEMBL4328541

O=C(c1cc(Cl)c(Cl)c(Cl)c1)c1cc(Cl)c(Cl)c(Cl)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.48
HSD17B10 Q99714 5/20 0.48
CYP3A4 P08684 3/20 0.48
CRHBP P24387 1/20 0.48
CRHR2 Q13324 1/20 0.48
SRD5A2 P31213 3/20 0.46
ALDH1A1 P00352 3/20 0.45
TTR P02766 1/20 0.44
TSHR P16473 5/20 0.42
CASP1 P29466 1/20 0.41
VCAM1 P19320 1/20 0.39
MAPK1 P28482 2/20 0.38
HSP90AA1 P07900 1/20 0.38
HTR3E A5X5Y0 1/20 0.37
HTR3B O95264 1/20 0.37
HTR3A P46098 1/20 0.37
HTR3D Q70Z44 1/20 0.37
HTR3C Q8WXA8 1/20 0.37
CNR1 P21554 1/20 0.36
CNR2 P34972 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7263572 0.80 TTR (0.68) HPGDHSD17B10CYP3A4CRHBPCRHR2
SCHEMBL3422274 0.80 TTR (0.68) HPGDHSD17B10CYP3A4SRD5A2ALDH1A1
SCHEMBL983196 0.80 HPGD (0.46) HPGDHSD17B10CYP3A4CRHBPCRHR2
SCHEMBL7348279 0.80 HPGD (0.46) HPGDHSD17B10CYP3A4CRHBPCRHR2
SCHEMBL3130004 0.78 LMNA (0.47) HPGDHSD17B10CYP3A4CRHBPCRHR2
SCHEMBL7779178 0.78 CA5A (0.50) HPGDHSD17B10CYP3A4CRHBPCRHR2
SCHEMBL2967888 0.78 HPGD (0.43) HPGDHSD17B10CYP3A4CRHBPCRHR2
SCHEMBL5981527 0.78 HSD11B1 (0.52) CYP3A4SRD5A2ALDH1A1TTRTSHR
SCHEMBL11048208 0.78 HPGD (0.43) HPGDHSD17B10CYP3A4CRHBPCRHR2
Fluoride SCHEMBL27668632 0.78 TTR (0.65) HPGDHSD17B10CYP3A4CRHBPCRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7635744-B2 Trifluorovinyloxy monomers and polymers GENERAL ELECTRIC COMPANY (US) 2009-12-22 US disclosed
US-20070238856-A1 Trifluorovinyloxy monomers and polymers GENERAL ELECTRIC COMPANY 2007-10-11 US disclosed