Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | P2RY10 | O00398 | 2/20 | 0.36 |
| ▸ | GPR174 | Q9BXC1 | 2/20 | 0.36 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31734856 | 0.80 | ITGB3 (0.57) | SLC7A5ITGB3ITGA2B | |
| SCHEMBL3972716 | 0.79 | SLC7A5 (0.46) | SLC7A5ITGB3ITGA2B | |
| SCHEMBL3841016 | 0.75 | TRPA1 (0.53) | TAAR1MAPK1L3MBTL1TSHRTDP1 | |
| SCHEMBL3228373 | 0.75 | TAAR1 (0.51) | TAAR1MAPK1L3MBTL1TSHRTDP1 | |
| SCHEMBL611119 | 0.71 | TAAR1 (0.45) | TAAR1MAPK1L3MBTL1TSHRTDP1 | |
| SCHEMBL3837370 | 0.71 | TAAR1 (0.41) | TAAR1MAPK1L3MBTL1TSHRTDP1 | |
| SCHEMBL17974304 | 0.70 | ACHE (0.48) | TAAR1MAPK1L3MBTL1TSHRTDP1 | |
| SCHEMBL17974305 | 0.69 | ACHE (0.45) | TAAR1MAPK1L3MBTL1TSHRTDP1 | |
| SCHEMBL31506209 | 0.69 | LTA4H (0.47) | TAAR1MAPK1L3MBTL1TSHRTDP1 | |
| SCHEMBL31506033 | 0.69 | LTA4H (0.47) | TAAR1MAPK1L3MBTL1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091955-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | Acucela, Inc. (US) | 2009-08-26 | — | — | EP | disclosed |