SCHEMBL4329580

SCHEMBL4329580

CCOC(=O)C(CC(CC)c1ccc(OC)cc1)c1ncco1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.44
CTSA P10619 6/20 0.41
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ALDH1A1 P00352 1/20 0.36
GAA P10253 1/20 0.36
ALOX15 P16050 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
NPC1 O15118 1/20 0.35
HSP90AA1 P07900 1/20 0.35
MAPT P10636 1/20 0.35
RAB9A P51151 1/20 0.35
FAAH O00519 1/20 0.35
AKR1C3 P42330 3/20 0.35
AKR1C2 P52895 3/20 0.35
AKR1C1 Q04828 1/20 0.35
PTGS1 P23219 1/20 0.35
TARBP2 Q15633 1/20 0.34
PDCD4 Q53EL6 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4327338 0.89 FFAR1 (0.48) FFAR1CTSAL3MBTL1FAAHAKR1C3
SCHEMBL4333159 0.88 FFAR2 (0.39) FFAR1CTSAMEN1KMT2ATDP1
SCHEMBL4343287 0.88 CTSA (0.41) CTSA
SCHEMBL4340146 0.86 FFAR1 (0.43) FFAR1CTSAFAAH
SCHEMBL4323851 0.85 CTSA (0.39) CTSAMEN1KMT2ATDP1ALDH1A1
SCHEMBL4331353 0.74 CTSA (0.41) CTSA
SCHEMBL4329821 0.74 FFAR2 (0.41) CTSAMEN1KMT2AAKR1C3AKR1C2
SCHEMBL4335078 0.74 CTSA (0.38) FFAR1CTSAMEN1KMT2ATDP1
SCHEMBL4341790 0.73 CTSA (0.40) CTSAMEN1KMT2ATDP1ALDH1A1
SCHEMBL4322072 0.73 CTSA (0.40) CTSAMEN1KMT2ATDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7521563-B2 Hydroxamic acid derivative and medicine containing the same as active ingredient SHIZUOKA COFFEIN CO., LTD. (JP) 2009-04-21 US disclosed
US-20070208065-A1 Hydroxamic Acid Derivative and Medicine Containing the Same as Active Ingredient SHIZUOKA COFFEIN CO., LTD. (JP) 2007-09-06 US disclosed
EP-1787986-A1 HYDROXAMIC ACID DERIVATIVE AND MEDICINE CONTAINING THE SAME AS ACTIVE INGREDIENT SHIZUOKA COFFEIN CO., LTD. (JP) 2007-05-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070208065-A1 Hydroxamic Acid Derivative and Medicine Containing the Same as Active Ingredient IL6, IL1A, TNF FFAR1 1103/4885CTSA 1028/4885MEN1 3484/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.