SCHEMBL4333159

SCHEMBL4333159

CCOC(=O)C(CC(CC)c1ccc(Cl)cc1)c1ncco1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR2 O15552 2/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
GPR119 Q8TDV5 4/20 0.37
LMNA P02545 2/20 0.37
ALDH1A1 P00352 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
MAPT P10636 1/20 0.37
CTSA P10619 3/20 0.36
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
MAPK1 P28482 1/20 0.35
KMT2A Q03164 2/20 0.34
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
GAA P10253 1/20 0.33
RAB9A P51151 1/20 0.33
MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4343287 0.89 CTSA (0.41) CTSA
SCHEMBL4329580 0.88 FFAR1 (0.44) ALDH1A1TDP1MAPTCTSAKMT2A
SCHEMBL4329821 0.87 FFAR2 (0.41) FFAR2CYP3A4CYP2C9LMNACTSA
SCHEMBL4322294 0.84 FFAR2 (0.44) FFAR2CTSA
SCHEMBL4337653 0.81 GPR119 (0.41) FFAR2CYP3A4CYP2C9GPR119LMNA
SCHEMBL4327338 0.76 FFAR1 (0.48) CTSAL3MBTL1FFAR1
SCHEMBL7457511 0.76 FFAR2 (0.40) FFAR2CYP3A4CYP2C9GPR119LMNA
SCHEMBL4331353 0.75 CTSA (0.41) CTSA
SCHEMBL4335078 0.75 CTSA (0.38) TDP1MAPTCTSAKMT2AMEN1
SCHEMBL7462050 0.74 FFAR2 (0.38) FFAR2CYP3A4CYP2C9GPR119LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7521563-B2 Hydroxamic acid derivative and medicine containing the same as active ingredient SHIZUOKA COFFEIN CO., LTD. (JP) 2009-04-21 US disclosed
US-20070208065-A1 Hydroxamic Acid Derivative and Medicine Containing the Same as Active Ingredient SHIZUOKA COFFEIN CO., LTD. (JP) 2007-09-06 US disclosed
EP-1787986-A1 HYDROXAMIC ACID DERIVATIVE AND MEDICINE CONTAINING THE SAME AS ACTIVE INGREDIENT SHIZUOKA COFFEIN CO., LTD. (JP) 2007-05-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070208065-A1 Hydroxamic Acid Derivative and Medicine Containing the Same as Active Ingredient IL6, IL1A, TNF FFAR2 1603/4885CYP3A4 2548/4885CYP2C9 1837/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.