Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 14/20 | 0.76 |
| ▸ | ATP4B | P51164 | 14/20 | 0.76 |
| ▸ | NPC1 | O15118 | 3/20 | 0.76 |
| ▸ | RAB9A | P51151 | 3/20 | 0.76 |
| ▸ | MAPT | P10636 | 2/20 | 0.76 |
| ▸ | ACR | P10323 | 2/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.48 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4322678 | 0.91 | ATP4A (0.70) | ATP4AATP4BNPC1RAB9AMAPT | |
| SCHEMBL4329794 | 0.90 | ATP4A (0.66) | ATP4AATP4BNPC1RAB9AMAPT | |
| SCHEMBL4330723 | 0.87 | PRSS1 (0.61) | ATP4AATP4BNPC1RAB9AMAPT | |
| SCHEMBL4109611 | 0.87 | ATP4A (1.00) | ATP4AATP4BNPC1RAB9AMAPT | |
| Bromide SCHEMBL826017 | 0.86 | ATP4A (1.00) | ATP4AATP4BNPC1RAB9AMAPT | |
| SCHEMBL4324204 | 0.84 | ATP4A (0.55) | ATP4AATP4BNPC1RAB9AMAPT | |
| SCHEMBL4333457 | 0.83 | ATP4A (0.57) | ATP4AATP4BNPC1RAB9AMAPT | |
| SCHEMBL4326705 | 0.83 | ATP4A (0.55) | ATP4AATP4BNPC1RAB9AMAPT | |
| SCHEMBL4331871 | 0.78 | ADORA3 (0.58) | NPC1RAB9AMAPTMEN1KDM4E | |
| SCHEMBL4342349 | 0.76 | ATP4A (0.56) | ATP4AATP4BNPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | claimed |
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | disclosed |