Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.54 |
| ▸ | AGXT | P21549 | 3/20 | 0.51 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.45 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.45 |
| ▸ | CHKA | P35790 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4337043 | 0.87 | HTR7 (0.50) | ALDH1A1MAPTSIGMAR1DRD2DRD3 | |
| SCHEMBL4331617 | 0.87 | AGXT (0.55) | PRMT6AGXTL3MBTL3L3MBTL1SIGMAR1 | |
| SCHEMBL4321581 | 0.84 | CHKA (0.46) | L3MBTL3L3MBTL1MBTD1TP53BP1CHKA | |
| SCHEMBL4332085 | 0.83 | CHKA (0.48) | PRMT6L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL27829456 | 0.82 | RORC (0.46) | USP2MAPTGAAHSD17B10 | |
| SCHEMBL541280 | 0.76 | L3MBTL1 (0.41) | PRMT6AGXTL3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL10244433 | 0.76 | PRMT6 (0.61) | PRMT6AGXTL3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL4806907 | 0.76 | AGXT (0.58) | PRMT6AGXTL3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL4320115 | 0.75 | TAAR1 (0.41) | KDM4EMEN1KMT2AACHE | |
| SCHEMBL160644 | 0.75 | PRMT6 (0.42) | PRMT6L3MBTL3L3MBTL1MBTD1CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009145360-A1 | BENZENE OR THIOPHENE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R-TECH UENO, LTD. (JP) | 2009-12-03 | — | — | WO | claimed |
| WO-2009145360-A1 | BENZENE OR THIOPHENE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R-TECH UENO, LTD. (JP) | 2009-12-03 | — | — | WO | disclosed |