Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INPPL1 | O15357 | 12/20 | 0.45 |
| ▸ | INPP5A | Q14642 | 6/20 | 0.45 |
| ▸ | INPP5B | P32019 | 2/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | STAT5A | P42229 | 3/20 | 0.36 |
| ▸ | STAT5B | P51692 | 3/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4580479 | 0.78 | INPPL1 (0.52) | INPPL1INPP5AINPP5BAKT1ALDH1A1 | |
| SCHEMBL2991418 | 0.77 | INPPL1 (0.42) | INPPL1INPP5AINPP5BAKT1SRC | |
| SCHEMBL7668780 | 0.74 | ALDH1A1 (0.47) | KDM4EUSP2ALDH1A1HPGD | |
| SCHEMBL21407745 | 0.72 | NPC1 (0.50) | INPPL1INPP5AINPP5BAKT1FDPS | |
| SCHEMBL15315299 | 0.71 | INPPL1 (0.58) | INPPL1INPP5AINPP5BAKT1SRC | |
| SCHEMBL2127225 | 0.70 | LMNA (0.64) | INPPL1INPP5AINPP5BAKT1SRC | |
| SCHEMBL1696485 | 0.69 | INPPL1 (0.41) | INPPL1INPP5AINPP5BAKT1SRC | |
| SCHEMBL258268 | 0.68 | INPPL1 (0.54) | INPPL1INPP5AINPP5BAKT1SRC | |
| SCHEMBL30023648 | 0.68 | INPPL1 (0.54) | INPPL1INPP5AINPP5BAKT1SRC | |
| Hydrochloric Acid SCHEMBL29188656 | 0.68 | LMNA (0.62) | INPPL1INPP5AINPP5BAKT1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2048140-A1 | Deuterated chemiluminescent 1,2-dioxetanes | Giri, Brij P. (US) | 2009-04-15 | — | — | EP | disclosed |
| EP-1453822-A4 | DEUTERIUM-BASED CHEMILUMINESCENT 1,2-DIOXETANES | GIRI BRIJ P (US) | 2004-11-24 | — | — | EP | disclosed |
| EP-1453822-A2 | DEUTERIUM-BASED CHEMILUMINESCENT 1,2-DIOXETANES | Giri, Brij P. (US) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003054506-A2 | DEUTERIUM-BASED CHEMILUMINESCENT 1,2-DIOXETANES | GIRI BRIJ PAL (US) | 2003-07-03 | — | — | WO | disclosed |