Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | F9 | P00740 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | PPIA | P62937 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4334583 | 0.85 | PPARG (0.43) | PKMALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL4335538 | 0.85 | KMT2A (0.45) | ALDH1A1SMN1; SMN2RAB9ANPC1HTT | |
| SCHEMBL4340671 | 0.82 | OPRK1 (0.44) | ALDH1A1SMN1; SMN2RAB9ANPC1HTT | |
| SCHEMBL4347051 | 0.81 | POLB (0.41) | PKMRECQLPOLBP2RY1PPIA | |
| SCHEMBL4329791 | 0.81 | LMNA (0.44) | ALDH1A1SMN1; SMN2RECQLRAB9ANPC1 | |
| SCHEMBL6727260 | 0.80 | NPC1 (0.47) | ALDH1A1SMN1; SMN2RAB9ANPC1HTT | |
| SCHEMBL4341327 | 0.79 | ALOX15 (0.38) | PKMALDH1A1SMN1; SMN2NPC1F9 | |
| SCHEMBL6724483 | 0.78 | MTNR1B (0.48) | PKMSMN1; SMN2RECQLRAB9ANPC1 | |
| SCHEMBL4341658 | 0.78 | MAPT (0.48) | ALDH1A1SMN1; SMN2RAB9ANPC1HTT | |
| SCHEMBL4327192 | 0.77 | CYP1A2 (0.56) | ALDH1A1SMN1; SMN2RAB9ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-20040102634-A1 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2004-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102634-A1 | Carboxylic acid derivative and salt thereof | GPR119, IRS1, SLC5A1 | PKM 4339/4885ALDH1A1 844/4885SMN1; SMN2 3054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.