SCHEMBL4334665

SCHEMBL4334665

CCC(CC(NC(=O)c1ccc(NCC2CNc3nc(N)[nH]c(=O)c3N2)cc1)C(=O)O)C(=O)O

nearest known ligand 0.76

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ SOST Q9BQB4 1/20 0.76
▸ FPGS Q05932 2/20 0.75
▸ GART P22102 5/20 0.57
▸ DHFR P00374 1/20 0.51
▸ ATIC P31939 4/20 0.49
▸ MTHFD1 P11586 1/20 0.49
▸ NOS3 P29474 1/20 0.48
▸ NOS1 P29475 1/20 0.48
▸ NOS2 P35228 1/20 0.48
▸ LMNA P02545 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4126044 0.93 SOST (0.77) SOSTFPGSGARTDHFRATIC
SCHEMBL27363888 0.92 FPGS (0.75) SOSTFPGSGARTDHFRATIC
SCHEMBL3953439 0.91 SOST (0.78) SOSTFPGSGARTDHFRATIC
SCHEMBL15121249 0.91 SOST (0.78) SOSTFPGSGARTDHFRATIC
SCHEMBL50298 0.91 SOST (0.78) SOSTFPGSGARTDHFRATIC
SCHEMBL716106 0.91 SOST (0.78) SOSTFPGSGARTDHFRATIC
SCHEMBL27708884 0.90 SOST (0.77) SOSTFPGSGARTDHFRATIC
SCHEMBL28469783 0.90 SOST (0.77) SOSTFPGSGARTDHFRATIC
SCHEMBL28206357 0.90 SOST (0.79) SOSTFPGSGARTDHFRATIC
SCHEMBL6493083 0.88 SOST (0.75) SOSTFPGSGARTDHFRATIC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4210681-A1 DISSOLVABLE MATRICES Thorne Healthtech, Inc. (US) 2023-07-19 — — EP disclosed
WO-2022055985-A1 DISSOLVABLE MATRICES NUTRATIVA LLC (US) 2022-03-17 — — WO disclosed
WO-2009052186-A1 METABOLOMICS-BASED IDENTIFICATION OF DISEASE-CAUSING AGENTS GEORGIA TECH RESEARCH CORPORATION (US) 2009-04-23 — — WO disclosed
WO-2001056385-A1 METHODS AND COMPOSITIONS FOR ENHANCING FORMYLTETRAHYDROPTEROYLPOLYGLUTAMATE IN PLANTS NONOMURA ARTHUR M (US) 2001-08-09 — — WO disclosed
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