Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOST | Q9BQB4 | 1/20 | 0.75 |
| ▸ | FPGS | Q05932 | 2/20 | 0.74 |
| ▸ | GART | P22102 | 5/20 | 0.56 |
| ▸ | DHFR | P00374 | 1/20 | 0.51 |
| ▸ | MTHFD1 | P11586 | 1/20 | 0.49 |
| ▸ | ATIC | P31939 | 4/20 | 0.49 |
| ▸ | NOS1 | P29475 | 2/20 | 0.48 |
| ▸ | NOS3 | P29474 | 1/20 | 0.48 |
| ▸ | NOS2 | P35228 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15121249 | 0.90 | SOST (0.78) | SOSTFPGSGARTDHFRMTHFD1 | |
| SCHEMBL50298 | 0.90 | SOST (0.78) | SOSTFPGSGARTDHFRMTHFD1 | |
| SCHEMBL3953439 | 0.90 | SOST (0.78) | SOSTFPGSGARTDHFRMTHFD1 | |
| SCHEMBL716106 | 0.90 | SOST (0.78) | SOSTFPGSGARTDHFRMTHFD1 | |
| SCHEMBL28469783 | 0.89 | SOST (0.77) | SOSTFPGSGARTDHFRMTHFD1 | |
| SCHEMBL27708884 | 0.89 | SOST (0.77) | SOSTFPGSGARTDHFRMTHFD1 | |
| SCHEMBL28206357 | 0.89 | SOST (0.79) | SOSTFPGSGARTDHFRMTHFD1 | |
| SCHEMBL4334665 | 0.88 | SOST (0.76) | SOSTFPGSGARTDHFRMTHFD1 | |
| SCHEMBL10464162 | 0.88 | SOST (0.85) | SOSTFPGSGARTDHFRMTHFD1 | |
| SCHEMBL20509041 | 0.88 | SOST (0.85) | SOSTFPGSGARTDHFRMTHFD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6849628-B2 | Optically active compounds | THE UNIVERSITY OF STRATHCLYDE (GB) | 2005-02-01 | — | — | US | disclosed |
| US-6500829-B1 | MIXTURES OF STEREOISOMERS USED AS ANTICARCINOGENIC AGENTS OR FOR THE TREATMENT OF VITAMIN DEFICIENCY | UNIVERSITY OF STRATHCLYDE (GB) | 2002-12-31 | — | — | US | disclosed |