SCHEMBL4335756

SCHEMBL4335756

O=P(O)(O)N(c1ccc(O)cc1)P(=O)(O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.40
CA1 P00915 3/20 0.40
CA2 P00918 3/20 0.40
MAPT P10636 3/20 0.40
KDM4E B2RXH2 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
LMNA P02545 2/20 0.40
HPGD P15428 2/20 0.40
HSD17B10 Q99714 2/20 0.40
CA3 P07451 2/20 0.40
CYP3A4 P08684 2/20 0.40
TYR P14679 2/20 0.40
CA4 P22748 2/20 0.40
CA5A P35218 2/20 0.40
BLM P54132 2/20 0.40
PMP22 Q01453 2/20 0.40
HIF1A Q16665 2/20 0.40
CA9 Q16790 2/20 0.40
CA14 Q9ULX7 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL915095 0.78 ALDH1A1 (0.41) CA12CA1CA2MAPTKDM4E
SCHEMBL3065169 0.77 MEN1 (0.54) CA12CA2MEN1KMT2AHPGD
Hydroquinone SCHEMBL329315 0.74 CA12 (0.61) CA12CA1CA2MAPTKDM4E
Hydroquinone SCHEMBL131228 0.74 CA12 (0.61) CA12CA1CA2MAPTKDM4E
Methane SCHEMBL3421099 0.73 TSHR (0.50) CA12CA1CA2MEN1KMT2A
Hydroquinone SCHEMBL14718054 0.69 ESR1 (0.56) CA12CA1CA2MAPTKDM4E
Phosphoric Acid SCHEMBL29167223 0.69 CA12 (0.44) CA12CA1CA2MAPTKDM4E
Hydroquinone SCHEMBL5705489 0.67 CA1 (0.50) CA12CA1CA2MAPTKDM4E
SCHEMBL279529 0.66 ALOX15 (0.57) CA12CA1CA2MAPTKDM4E
SCHEMBL3066343 0.65 MEN1 (0.46) CA2MAPTMEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8815834-B2 Use of dendrimers to stimulate cell growth CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2014-08-26 US disclosed
US-20090142316-A1 Use of Dendrimers to Stimulate Cell Growth CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2009-06-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090142316-A1 Use of Dendrimers to Stimulate Cell Growth HDGF, CD40LG, PPIP5K2 CA12 758/4885CA1 1683/4885CA2 571/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.