Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Ethylene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 known ✓ | P25103 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL820677 | 0.83 | HTR2A (0.35) | HTR6HTR2ASIGMAR1 | |
| Ethylene SCHEMBL4339097 | 0.80 | HTR2A (0.34) | HTR6HTR2ASIGMAR1 | |
| SCHEMBL3383305 | 0.77 | HTR2A (0.38) | HTR6HTR2ATACR1SIGMAR1 | |
| Ethylene SCHEMBL819410 | 0.77 | HTR2A (0.38) | HTR6HTR2ASIGMAR1 | |
| SCHEMBL1921591 | 0.77 | HTR2A (0.38) | HTR6HTR2ATACR1SIGMAR1 | |
| SCHEMBL3383301 | 0.77 | HTR2A (0.38) | HTR6HTR2ATACR1SIGMAR1 | |
| Ethylene SCHEMBL4337196 | 0.77 | HTR2A (0.38) | HTR6HTR2ASIGMAR1 | |
| SCHEMBL9860034 | 0.75 | HTR2A (0.37) | HTR6HTR2ATACR1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8853570 | 0.75 | HTR6 (0.37) | HTR6HTR2ATACR1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8853905 | 0.75 | HTR2A (0.34) | HTR6HTR2ATACR1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592403-B2 | Ethylene polymer, preparation process thereof and molded articles of the same | MITSUI CHEMICALS, INC. (JP) | 2009-09-22 | — | — | US | claimed |
| US-7592403-B2 | Ethylene polymer, preparation process thereof and molded articles of the same | MITSUI CHEMICALS, INC. (JP) | 2009-09-22 | — | — | US | disclosed |
| US-20050267273-A1 | Ethylene polymer, preparation process thereof and molded articles of the same | MITSUI CHEMICALS, INC. | 2005-12-01 | — | — | US | disclosed |
| EP-1231229-A2 | Ethylene polymer, preparation process thereof and molded articles of the same | Mitsui Chemicals, Inc. (JP) | 2002-08-14 | — | — | EP | disclosed |
| US-20020107343-A1 | Ethylene polymer, preparation process thereof and molded articles of the same | MITSUI CHEMICALS, INC. | 2002-08-08 | — | — | US | disclosed |