Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 known ✓ | P25103 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6358818 | 0.83 | HTR2A (0.34) | HTR6TACR1HTR2ARETSIGMAR1 | |
| Hydrochloric Acid SCHEMBL8853892 | 0.83 | HTR2A (0.34) | HTR6TACR1HTR2ARETSIGMAR1 | |
| Hydrochloric Acid SCHEMBL8853905 | 0.83 | HTR2A (0.34) | HTR6TACR1HTR2ARETSIGMAR1 | |
| SCHEMBL3383301 | 0.75 | HTR2A (0.38) | HTR6TACR1HTR2ARETSIGMAR1 | |
| SCHEMBL3383305 | 0.75 | HTR2A (0.38) | HTR6TACR1HTR2ARETSIGMAR1 | |
| SCHEMBL1921591 | 0.75 | HTR2A (0.38) | HTR6TACR1HTR2ARETSIGMAR1 | |
| Ethylene SCHEMBL4337290 | 0.75 | HTR6 (0.38) | HTR6TACR1HTR2ASIGMAR1 | |
| Ethylene SCHEMBL820677 | 0.75 | HTR2A (0.35) | HTR6HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL7766782 | 0.74 | RET (0.34) | HTR6TACR1HTR2ARET | |
| SCHEMBL9860034 | 0.74 | HTR2A (0.37) | HTR6TACR1HTR2ARETSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5604170-A | EFFECTIVE CATALYST SUPPORT SATISFYING CERTAIN REQUISITES: PARTICLE DIAMETER, SPECIFIC SURFACE AREA, PORE VOLUME, SPECIFIC GRAVITY; SUBJECTED TO ULTRASONIC DISINTEGRATION | NIPPON OIL COMPANY, LIMITED (JP) | 1997-02-18 | — | — | US | disclosed |
| EP-0411937-A2 | Catalyst for polymerization of olefins | Tonen Corporation (JP) | 1991-02-06 | — | — | EP | disclosed |