Ethylene

Ethylene

SCHEMBL820677

C=C.[Cl-].[Zr+]CC(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Ethylene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.35
HTR6 P50406 1/20 0.35
SIGMAR1 Q99720 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL4337290 0.83 HTR6 (0.38) HTR2AHTR6SIGMAR1
Ethylene SCHEMBL819410 0.80 HTR2A (0.38) HTR2AHTR6SIGMAR1
SCHEMBL3383305 0.77 HTR2A (0.38) HTR2AHTR6SIGMAR1
Ethylene SCHEMBL820681 0.77 HTR2A (0.42) HTR2AHTR6SIGMAR1
SCHEMBL1921591 0.77 HTR2A (0.38) HTR2AHTR6SIGMAR1
Ethylene SCHEMBL4339097 0.77 HTR2A (0.34) HTR2AHTR6SIGMAR1
SCHEMBL3383301 0.77 HTR2A (0.38) HTR2AHTR6SIGMAR1
Hydrochloric Acid SCHEMBL8568820 0.76 HTR2A (0.41) HTR2AHTR6SIGMAR1
SCHEMBL9860034 0.75 HTR2A (0.37) HTR2AHTR6SIGMAR1
Hydrochloric Acid SCHEMBL6358818 0.75 HTR2A (0.34) HTR2AHTR6SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3480258-B1 SOLID MAO COMPOSITION CONTAINING AL2O3 AND METHOD FOR PRODUCING SAME TOSOH FINECHEM CORP (JP) 2023-12-20 EP disclosed
US-10730969-B2 Solid MAO composition containing Al2O3 and method for producing same TOSOH FINECHEM CORPORATION (JP) 2020-08-04 US disclosed
EP-3480258-A1 SOLID MAO COMPOSITION CONTAINING AL2O3 AND METHOD FOR PRODUCING SAME Tosoh Finechem Corporation (JP) 2019-05-08 EP disclosed
US-20180355077-A1 SOLID MAO COMPOSITION CONTAINING AL2O3 AND METHOD FOR PRODUCING SAME TOSOH FINECHEM CORPORATION (JP) 2018-12-13 US disclosed
EP-2570437-B1 SOLID SUPPORT-POLYMETHYLALUMINOXANE COMPLEX, METHOD FOR PRODUCING SAME, OLEFIN POLYMERIZATION CATALYST, AND METHOD FOR PRODUCING POLYOLEFIN TOSOH FINECHEM CORP (JP) 2018-07-04 EP disclosed
EP-2360191-B1 SOLID POLYMETHYLALUMINOXANE COMPOSITION AND PROCESS FOR PRODUCING SAME TOSOH FINECHEM CORP (JP) 2017-03-29 EP disclosed
EP-2862889-B1 METHOD FOR PRODUCING SOLID POLYMETHYLALUMINOXANE COMPOSITION HAVING SMALL PARTICLE DIAMETER TOSOH FINECHEM CORP (JP) 2017-01-04 EP disclosed
US-9340630-B2 Method for manufacturing a small particle diameter product of solid polymethylaluminoxane composition TOSOH FINECHEM CORPORATION (JP) 2016-05-17 US disclosed
EP-2862889-A1 METHOD FOR PRODUCING SOLID POLYMETHYLALUMINOXANE COMPOSITION HAVING SMALL PARTICLE DIAMETER Tosoh Finechem Corporation (JP) 2015-04-22 EP disclosed
US-8975209-B2 Solid support-polymethylaluminoxane complex, method for producing same, olefin polymerization catalyst, and method for producing polyolefin TOSOH FINECHEM CORPORATION (JP) 2015-03-10 US disclosed
US-20150057418-A1 METHOD FOR MANUFACTURING A SMALL PARTICLE DIAMETER PRODUCT OF SOLID POLYMETHYLALUMINOXANE COMPOSITION TOSOH FINECHEM CORPORATION (JP) 2015-02-26 US disclosed
EP-1728795-B1 POLYMETHYLALUMINOXANE PRODUCT, PROCESS FOR PRODUCING THE SAME, POLYMERIZATION CATALYST, AND METHOD OF POLYMERIZING OLEFIN TOSOH FINECHEM CORP (JP) 2014-02-12 EP disclosed
US-8404880-B2 Solid polymethylaluminoxane composition and method for manufacturing same TOSOH FINECHEM CORPORATION (JP) 2013-03-26 US disclosed
EP-2570437-A1 SOLID SUPPORT-POLYMETHYLALUMINOXANE COMPLEX, METHOD FOR PRODUCING SAME, OLEFIN POLYMERIZATION CATALYST, AND METHOD FOR PRODUCING POLYOLEFIN Tosoh Finechem Corporation (JP) 2013-03-20 EP disclosed
US-20130059990-A1 SOLID SUPPORT-POLYMETHYLALUMINOXANE COMPLEX, METHOD FOR PRODUCING SAME, OLEFIN POLYMERIZATION CATALYST, AND METHOD FOR PRODUCING POLYOLEFIN TOSOH FINECHEM CORPORATION (JP) 2013-03-07 US disclosed
US-20110282017-A1 SOLID POLYMETHYLALUMINOXANE COMPOSITION AND METHOD FOR MANUFACTURING SAME TOSOH FINECHEM CORPORATION (JP) 2011-11-17 US disclosed
EP-2360191-A1 SOLID POLYMETHYLALUMINOXANE COMPOSITION AND PROCESS FOR PRODUCING SAME Tosoh Finechem Corporation (JP) 2011-08-24 EP disclosed
US-7910764-B2 Polymethylaluminoxane preparation, method of producing the same, polymerization catalyst, and polymerization method of olefins TOSOH FINECHEM CORPORATION (JP) 2011-03-22 US disclosed
US-20070197745-A1 Polymethylaluminoxane preparation, method of producing the same, polymerization catalyst, and polymerization method of olefins TOSOH FINECHEM CORPORATION (JP) 2007-08-23 US disclosed
EP-1728795-A1 POLYMETHYLALUMINOXANE PRODUCT, PROCESS FOR PRODUCING THE SAME, POLYMERIZATION CATALYST, AND METHOD OF POLYMERIZING OLEFIN Tosoh Finechem Corporation (JP) 2006-12-06 EP disclosed