Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4338639 | 1.00 | CTSK (0.36) | CTSKPIN1NOTUMBTKNTRK1 | |
| SCHEMBL4338635 | 1.00 | CTSK (0.36) | CTSKPIN1NOTUMBTKNTRK1 | |
| SCHEMBL4351517 | 0.98 | CTSK (0.35) | CTSKPIN1NOTUMBTKNTRK1 | |
| SCHEMBL4351527 | 0.98 | CTSK (0.35) | CTSKPIN1NOTUMBTKNTRK1 | |
| SCHEMBL4351523 | 0.98 | CTSK (0.35) | CTSKPIN1NOTUMBTKNTRK1 | |
| SCHEMBL212721 | 0.94 | CTSK (0.35) | CTSKPIN1NOTUMNTRK1MET | |
| SCHEMBL212719 | 0.94 | CTSK (0.35) | CTSKPIN1NOTUMNTRK1MET | |
| SCHEMBL212720 | 0.94 | CTSK (0.35) | CTSKPIN1NOTUMNTRK1MET | |
| SCHEMBL210234 | 0.92 | PIN1 (0.38) | CTSKPIN1NOTUMNTRK1MET | |
| SCHEMBL210235 | 0.92 | PIN1 (0.38) | CTSKPIN1NOTUMNTRK1MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275537-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275537-A1 | Certain chemical entities, compositions, and methods | MYLK, MYH2, MYH10 | CTSK 1455/4885PIN1 4267/4885NOTUM 2164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.