Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 19/20 | 0.66 |
| ▸ | HDAC8 | Q9BY41 | 12/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 12/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.63 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.63 |
| ▸ | HDAC7 | Q8WUI4 | 8/20 | 0.63 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.63 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.63 |
| ▸ | HDAC9 | Q9UKV0 | 8/20 | 0.63 |
| ▸ | HDAC5 | Q9UQL6 | 8/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4327333 | 0.87 | CASP3 (0.52) | HDAC1HDAC8HDAC2HDAC6HDAC3 | |
| SCHEMBL4341819 | 0.85 | HDAC1 (0.64) | HDAC1HDAC8HDAC2HDAC6HDAC3 | |
| SCHEMBL4322293 | 0.85 | HDAC1 (0.64) | HDAC1HDAC8HDAC2HDAC6HDAC3 | |
| SCHEMBL4329577 | 0.83 | ENPP3 (0.46) | HDAC1HDAC8HDAC2HDAC6HDAC3 | |
| SCHEMBL4329469 | 0.79 | HDAC1 (0.65) | HDAC1HDAC8HDAC2HDAC6HDAC3 | |
| SCHEMBL2526301 | 0.79 | HDAC1 (0.65) | HDAC1HDAC8HDAC2HDAC6HDAC3 | |
| SCHEMBL2526073 | 0.77 | HDAC1 (0.47) | HDAC1HDAC8HDAC2HDAC6HDAC3 | |
| SCHEMBL3048357 | 0.76 | DAGLA (0.54) | HDAC1HDAC8HDAC2 | |
| SCHEMBL13732755 | 0.76 | ENPP3 (0.56) | — | |
| SCHEMBL2526068 | 0.75 | RXRA (0.61) | HDAC1HDAC8HDAC2HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070208065-A1 | Hydroxamic Acid Derivative and Medicine Containing the Same as Active Ingredient | SHIZUOKA COFFEIN CO., LTD. (JP) | 2007-09-06 | — | — | US | claimed |
| EP-1787986-A1 | HYDROXAMIC ACID DERIVATIVE AND MEDICINE CONTAINING THE SAME AS ACTIVE INGREDIENT | SHIZUOKA COFFEIN CO., LTD. (JP) | 2007-05-23 | — | — | EP | claimed |
| US-7521563-B2 | Hydroxamic acid derivative and medicine containing the same as active ingredient | SHIZUOKA COFFEIN CO., LTD. (JP) | 2009-04-21 | — | — | US | disclosed |
| US-20070208065-A1 | Hydroxamic Acid Derivative and Medicine Containing the Same as Active Ingredient | SHIZUOKA COFFEIN CO., LTD. (JP) | 2007-09-06 | — | — | US | disclosed |
| EP-1787986-A1 | HYDROXAMIC ACID DERIVATIVE AND MEDICINE CONTAINING THE SAME AS ACTIVE INGREDIENT | SHIZUOKA COFFEIN CO., LTD. (JP) | 2007-05-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208065-A1 | Hydroxamic Acid Derivative and Medicine Containing the Same as Active Ingredient | IL6, IL1A, TNF | HDAC1 27/4885HDAC8 104/4885HDAC2 69/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.